Evidence map›Paper›PMID 30392458›Full record

ArticleMolecular imaging

Magnetic Resonance Imaging for Characterization of a Chick Embryo Model of Cancer Cell Metastases.

Anne Herrmann, Arthur Taylor, Patricia Murray, Harish Poptani, Violaine Sée

Open access · goldAbstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Multi-parametric magnetic resonance imaging evaluation of a novelQuantitative imaging in medicine and surgery · 2025
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  8. A Modified Quadrature Birdcage Coil Incorporated With a Curved Feature forIEEE open journal of engineering in medicine and biology · 2024
    Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Anne Herrmann1 Department of Biochemistry, University of Liverpool, Liverpool, United Kingdom.
Arthur Taylor2 Centre for Preclinical Imaging, Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom.
Patricia Murray2 Centre for Preclinical Imaging, Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom.
Harish Poptani2 Centre for Preclinical Imaging, Department of Cellular and Molecular Physiology, University of Liverpool, Liverpool, United Kingdom.
Violaine Sée1 Department of Biochemistry, University of Liverpool, Liverpool, United Kingdom.
University of Liverpool · GB

Funding

Medical Research Council MR/K015931/1Medical Research Council MR/L012707/1
6 · The paper itself

Abstract

Metastasis is the most common cause of death for patients with cancer. To fully understand the steps involved in metastatic dissemination, in vivo models are required, of which murine ones are the most common. Therefore, preclinical imaging methods such as magnetic resonance imaging (MRI) have mainly been developed for small mammals and their potential to monitor cancer growth and metastasis in nonmammalian models is not fully harnessed. We have here used MRI to measure primary neuroblastoma tumor size and metastasis in a chick embryo model. We compared its sensitivity and accuracy to end-point fluorescence detection upon dissection. Human neuroblastoma cells labeled with green fluorescent protein (GFP) and micron-sized iron particles were implanted on the extraembryonic chorioallantoic membrane of the chick at E7. T

Indexed as

Magnetic Resonance ImagingAnimalsCarcinogenesisCell Line, TumorChick EmbryoChorioallantoic MembraneDisease Models, AnimalEmbryonic DevelopmentHumansIronNeoplasm MetastasisParticle SizeTumor BurdenIronchick embryoimaging metastasisin ovo imagingMRIneuroblastoma

Identifiers

PMID30392458
PMCPMC6236852
OpenAlexW2772037567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.