Evidence map›Paper›PMID 30392163›Full record

ArticlePediatric radiology2019

Susceptibility-weighted imaging of retinal hemorrhages in abusive head trauma.

Krishnamoorthy Thamburaj, Ajay Soni, Lori D Frasier, Kyaw N Tun, Sarah R Weber, Mark S Dias

Abstract read
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In one paragraph

Article in Pediatric radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Imaging of Abusive Head Trauma : A Radiologists' Perspective.Journal of Korean Neurosurgical Society · 2022
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Pediatric Abusive Head Trauma: A Systematic Review.Diagnostics (Basel, Switzerland) · 2021
    Review
  12. Article
  13. Ocular findings in the evaluation of abusive head trauma in children.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Krishnamoorthy ThamburajDepartment of Radiology, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, 500 University Drive, Hershey, PA, 17033, USA. kthamburaj@pennstatehealth.psu.edu.
Ajay SoniDepartment of Ophthalmology, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
Lori D FrasierDepartment of Pediatrics, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
Kyaw N TunDepartment of Radiology, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, 500 University Drive, Hershey, PA, 17033, USA.
Sarah R WeberDepartment of Ophthalmology, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
Mark S DiasDepartment of Neurosurgery, Penn State Health Milton S. Hershey Medical Center, Penn State College of Medicine, Hershey, PA, USA.
Penn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinal hemorrhages are one of the most important supportive evidences for abusive head trauma (AHT). Susceptibility-weighted imaging (SWI) is highly suited to identify various forms of intracranial hemorrhage in AHT. However its utility in imaging retinal hemorrhage is not well established.

objectiveSWI is a sensitive sequence for identifying retinal hemorrhage on MRI. MATERIALS AND

methodsIn this retrospective analysis, 26 consecutive infants and young children with a suspected admission diagnosis of AHT underwent indirect ophthalmoscopy and brain MRI protocol for AHT along with SWI. Brain susceptibility-weighted images of 14 age-matched children were used as controls. For detecting retinal hemorrhage, susceptibility-weighted images of patients and controls were reviewed randomly and independently by two neuroradiologists who were blinded to the history and ophthalmology findings. A pediatric ophthalmologist graded the indirect ophthalmoscopy images.

resultsA diagnosis of AHT was confirmed in all 26 cases from a multidisciplinary meeting. Indirect ophthalmoscopy images were available in 21 cases. Ophthalmoscopy was positive for retinal hemorrhage in the right eye in 18 cases (85.7%) and in the left eye in 16 cases (76.2%). On SWI, retinal hemorrhage was identified in the right eye in 9/21 cases (42.8%) and in the left eye in 8/21 cases (38.1%) of AHT. Analysis of SWI in 21 cases of AHT demonstrated a sensitivity of 50%, specificity of 100%, positive predictive value of 100% and negative predictive value of 32% for detecting retinal hemorrhage.

conclusionSWI is moderately sensitive and highly specific for identifying retinal hemorrhage in AHT. Further studies are needed to identify steps to improve the efficiency of SWI in detecting retinal hemorrhage.

Indexed as

ChildChild AbuseChild, PreschoolCraniocerebral TraumaFemaleHumansImage Interpretation, Computer-AssistedInfantMagnetic Resonance ImagingMaleOphthalmoscopyRetinal HemorrhageRetrospective StudiesSensitivity and SpecificityAbusive head traumaEyeInfantsMagnetic resonance imagingRetinal hemorrhageSusceptibility-weighted imaging

Identifiers

PMID30392163
OpenAlexW2898764421

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.