Evidence map›Paper›PMID 30392131›Full record

ArticlePsychopharmacology2019

Effects of adenosine A

Nicholas S Haynes, Casey E O'Neill, Benjamin D Hobson, Ryan K Bachtell

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Adenosine APsychopharmacology · 2026
    Article
  2. Article
  3. Allosteric Interactions between Adenosine AInternational journal of molecular sciences · 2021
    Review
  4. Adenosine ACells · 2020
    Review
  5. Functional and Neuroprotective Role of Striatal Adenosine AJournal of caffeine and adenosine research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicholas S HaynesDepartment of Psychology and Neuroscience; Center for Neuroscience, University of Colorado Boulder, UCB 345, Boulder, CO, 80309, USA.
Casey E O'NeillDepartment of Psychology and Neuroscience; Center for Neuroscience, University of Colorado Boulder, UCB 345, Boulder, CO, 80309, USA.
Benjamin D HobsonDepartment of Psychology and Neuroscience; Center for Neuroscience, University of Colorado Boulder, UCB 345, Boulder, CO, 80309, USA.
Ryan K BachtellDepartment of Psychology and Neuroscience; Center for Neuroscience, University of Colorado Boulder, UCB 345, Boulder, CO, 80309, USA. Ryan.Bachtell@Colorado.edu.ORCID http://orcid.org/0000-0001-5268-5927
University of Colorado Boulder · US

Funding

Adenosine Receptor Involvement in Methamphetamine Reward and RelapseR01DA033358 · NIDA · UNIVERSITY OF COLORADO · PI BACHTELL, RYAN K · 2013 to 2017
$1.9M
National Institute on Drug Abuse DA033358NIDA NIH HHS R01 DA033358
6 · The paper itself

Abstract

RATIONALE AND

objectivesAdenosine signaling through adenosine A

methodsSprague-Dawley rats were used to assess the differential effects of SCH 442416 and istradefylline that antagonize presynaptic and postsynaptic A

resultsNeither istradefylline nor SCH 442416 significantly altered basal locomotion. Istradefylline enhanced acute cocaine-induced locomotion but had no effect on the expression of locomotor sensitization. SCH 44216 had no effect on acute cocaine-induced locomotion but inhibited the expression of locomotor sensitization. Istradefylline was sufficient to induce cocaine seeking and augmented both cocaine-induced seeking and sucrose seeking. SCH 442416 inhibited cocaine-induced seeking, but had no effect on sucrose seeking and did not induce cocaine seeking when administered alone.

conclusionsThese findings demonstrate differential effects of two A

Indexed as

Adenosine A2 Receptor AntagonistsAnimalsCocaineCocaine-Related DisordersDose-Response Relationship, DrugDrug-Seeking BehaviorLocomotionMaleMotor ActivityRatsRats, Sprague-DawleySelf AdministrationAdenosine A2 Receptor AntagonistsCocaineBehavioral sensitizationKW 6002PsychostimulantPurinergic receptorsRelapse

Identifiers

PMID30392131
PMCPMC6401288
OpenAlexW2898832697

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.