Evidence map›Paper›PMID 30392043›Full record

ArticleInternational orthopaedics2019

Sagittal alignment assessment after short-segment lumbar fusion for degenerative disc disease.

Farzam Vazifehdan, Vasilios G Karantzoulis, Vasilios G Igoumenou

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In one paragraph

Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
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  4. Optimal cage biomaterials for fusion and subsidence outcomes in lumbar spinal fusion: a network meta-analysis of 4881 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  5. Impact of nonunion on patient-related outcomes after single level minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative disease: A propensity score-matched analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Farzam VazifehdanSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Stuttgart, Germany.
Vasilios G KarantzoulisSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Stuttgart, Germany.
Vasilios G IgoumenouSpine Center Stuttgart, Paulinenhilfe, Diakonie-Klinikum Stuttgart, Stuttgart, Germany. vasigou@med.uoa.gr.ORCID http://orcid.org/0000-0003-2922-3980
Diakonie-Klinikum Stuttgart · DENational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether differences in spinopelvic parameters, and especially spinopelvic alignment, could be associated with adjacent segment disease (ASD) or pseudarthrosis after short-segment lumbar fusion.

methodsRetrospective study of patients offered mono- or bisegmental transforaminal lumbar interbody fusion (TLIF) with polyetheretherketone (PEEK) or titanium cages, due to degenerative disease. Of 419 patients, 32 (7.6%) presented pseudarthrosis (nonunion group), 29 (6.9%) developed symptomatic ASD (ASD group), and 358 patients (85.5%) showed evidence of uncomplicated fusion (control group). Standard spinopelvic parameters were measured in all patients before and after surgery. The differences of the values within the parameters (Δ values) were also calculated. A comparative analysis within and among groups was performed. Patients were also analyzed by cage characteristics (large vs small, titanium vs PEEK).

resultsAll studied parameters changed significantly after surgery both in the control and ASD group, while in the nonunion group, only LL and PI-LL changed significantly (PI-LL increased from 10 ± 11° to 14 ± 10°, p = 0.008). Patients in the nonunion group presented greater SS before and after surgery, greater PI-LL after surgery, and higher PI, while ASD patients presented greater absolute mean ΔPT value. Age, size, and type of cage were not related to fusion, nonunion, or ASD.

conclusionsGreater SS, greater PI, and a PI-LL mismatch greater than 10° are associated with failed bony fusion, while ASD is related to a greater difference between the pre-operative and post-operative values of PT. Neither the type nor the size of cage seem to have a significant impact on either solid bony fusion, nonunion, or ASD rates. Thus, we recommend on the study of patients' sagittal alignment in the pre-operative setting even when treating patients with short-segment lumbar interbody fusion.

Indexed as

Intervertebral Disc DegenerationPseudarthrosisSpinal FusionAgedBenzophenonesFemaleHumansKetonesLumbar VertebraeLumbosacral RegionMaleMiddle AgedPolyethylene GlycolsPolymersPostoperative ComplicationsPostoperative PeriodBenzophenonesKetonespolyetheretherketonePolyethylene GlycolsPolymersDegenerative disc diseaseDisc herniationLumbar interbody fusionPEEKSagittal alignmentTitanium

Identifiers

PMID30392043
OpenAlexW2899057747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.