Evidence map›Paper›PMID 30391676›Full record

ArticleFree radical biology & medicine2019

Effects of oxygen challenging to tissue redox and pO

Ken-Ichiro Matsumoto, James B Mitchell, Murali C Krishna

Open access · greenAbstract read
In one paragraph

Article in Free radical biology & medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. EPR Spectra and Electron Spin Relaxation of OApplied magnetic resonance · 2021
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ken-Ichiro MatsumotoQuantitative RedOx Sensing Team, Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology, Chiba-shi, Chiba 263-8555, Japan. Electronic address: matsumoto.kenichiro@qst.go.jp.
James B MitchellRadiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1002, USA.
Murali C KrishnaRadiation Biology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1002, USA.
National Institutes of Health · USNational Institutes for Quantum and Radiological Science and Technology · JP

Funding

Time Domian Electron Paramagnetic Resonance ImagingZIABC010476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHERUKURI, MURALI · 2009 to 2025
$17.9M
Time Domian Electron Paramagnetic Resonance ImagingZ01BC010476 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHERUKURI, MURALI · 2003 to 2008
$1.7M
Radiolysis, Photolysis, Sonolysis and Sonoprotection ofZ01SC006387 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI MITCHELL, JAMES B · 1996 to 2008
$1.1M
Intramural NIH HHS Z01 BC010476Intramural NIH HHS Z01 SC006387
6 · The paper itself

Abstract

Nitroxide free radicals can serve as redox-sensitive MRI contrast agents useful to image the redox status of tissue of interest. In this study, the effect of oxygen content in the inspired gas on the kinetics of metabolism of three nitroxides has been evaluated in the muscle and tumor in mice. SCC tumors (approximate size of 1.0 cm

Indexed as

AnimalsContrast MediaCyclic N-OxidesFree RadicalsHumansKineticsMagnetic Resonance ImagingMiceMuscle, SkeletalNeoplasmsNitrogen OxidesOxidation-ReductionOximetryOxygenPyrrolidinesRadiation-Protective Agents3-carboxy-2,2,5,5-tetramethylpyrrolidin-1-yloxylContrast MediaCyclic N-OxidesFree RadicalsNitrogen OxidesnitroxylOxygenPyrrolidinesRadiation-Protective AgentsSpin LabelstempolMR redox imagingNitroxideRedox sensitive contrast agentT(1)-relaxivityTumor oxygenation

Identifiers

PMID30391676
PMCPMC8202967
OpenAlexW2898764857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.