ReviewHeart rhythm2019
Depolarization versus repolarization abnormality underlying inferolateral J-wave syndromes: New concepts in sudden cardiac death with apparently normal hearts.
Review in Heart rhythm, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern.JCI insight · 2019Pooled it
- Sudden cardiac death in early repolarization syndrome despite detailed evaluation for syncope: a case report.European heart journal. Case reports · 2026Article
- The History of the Precordial Early Repolarization and Sudden Death Syndrome, Lately Named Brugada Syndrome.Journal of clinical medicine · 2026Review
- Inferior-Lead Lambda (λ) Wave Revealing Critical Right Coronary Artery Stenosis: A Case Report.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2026Article
- A case report of J wave syndrome with abnormal potentials in both right and left ventricles and reversed J wave in lead V1.European heart journal. Case reports · 2026Article
- Dynamic Echocardiographic Changes Induced by Exercise in Healthy, Young Individuals with Early Repolarization Pattern.Diagnostics (Basel, Switzerland) · 2025Article
- Contributions of France to the field of clinical cardiac electrophysiology and pacing.Heart rhythm O2 · 2024Article
- Significance of J waves in unexplained ventricular fibrillation among elderly populations with various comorbidities.Heart rhythm O2 · 2024Article
- Exercise-Induced Electrocardiographic Changes in Healthy Young Males with Early Repolarization Pattern.Diagnostics (Basel, Switzerland) · 2024Article
- Lessons Learnt from Case Series of Out-of-hospital Cardiac Arrest and Unexpected Death after COVID-19 Vaccination.Internal medicine (Tokyo, Japan) · 2023Article
- Ventricular arrhythmias induced by phase 2 reentry in a patient with J-wave syndrome.HeartRhythm case reports · 2023Article
- Functional Epicardial Conduction Disturbances Due to a SCN5A Variant Associated With Brugada Syndrome.JACC. Clinical electrophysiology · 2023Article
- NovelExperimental and therapeutic medicine · 2023Article
- Trigger and Substrate Mapping and Ablation for Ventricular Fibrillation in the Structurally Normal Heart.Journal of cardiovascular development and disease · 2023Review
- The electrocardiogram in non-ischaemic-dilated cardiomyopathy.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- Ablation of ventricular arrhythmias in cardiogenetic diseases.European heart journal supplements : journal of the European Society of Cardiology · 2023Article
- A comprehensive framework for evaluation of high pacing frequency and arrhythmic optical mapping signals.Frontiers in physiology · 2023Article
- Fragmented QRS complex with an additional R-wave attenuated by short RR interval in a patient with acute pulmonary embolism and cardiogenic shock.Journal of geriatric cardiology : JGC · 2022Article
- Cardiac Morphofunctional Characteristics of Individuals with Early Repolarization Pattern: A Literature Review.Journal of cardiovascular development and disease · 2022Review
- European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022Article
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Authors and funding
18 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early repolarization indicates a distinct electrocardiographic phenotype affecting the junction between the QRS complex and the ST segment in inferolateral leads (inferolateral J-wave syndromes). It has been considered a benign electrocardiographic variant for decades, but recent clinical studies have demonstrated its arrhythmogenicity in a small subset, supported by experimental studies showing transmural dispersion of repolarization. Here we review the current knowledge and the issues of risk stratification that limit clinical management. In addition, we report on new mapping data of patients refractory to pharmacologic treatment using high-density electrogram mapping at the time of inscription of J wave. These data demonstrate that distinct substrates, delayed depolarization, and abnormal early repolarization underlie inferolateral J-wave syndromes, with significant implications. Finally, based on these data, we propose a new simplified mechanistic classification of sudden cardiac deaths without apparent structural heart disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.