Evidence map›Paper›PMID 30391275›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

The influenza season 2016/17 in Bucharest, Romania - surveillance data and clinical characteristics of patients with influenza-like illness admitted to a tertiary infectious diseases hospital.

Anca Drăgănescu, Oana Săndulescu, Dragoş Florea, Ovidiu Vlaicu, Anca Streinu-Cercel, Dan Oţelea, Victoria Aramă, Monica Luminiţa Luminos, Adrian Streinu-Cercel, Maria Niţescu and 3 more

Open access · goldAbstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Anca DrăgănescuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania.
Oana SăndulescuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Electronic address: oana.sandulescu@umfcd.ro.
Dragoş FloreaNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Ovidiu VlaicuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania.
Anca Streinu-CercelNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Dan OţeleaNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania.
Victoria AramăNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Monica Luminiţa LuminosNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Adrian Streinu-CercelNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Maria NiţescuNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Alina IvanciucCantacuzino Military-Medical Research-Development National Institute, Bucharest, Romania; Bucharest University, Faculty of Biology, Bucharest, Romania.
Rodica BacrubanNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania.
Daniela PiţigoiNational Institute for Infectious Diseases "Prof. Dr. Matei Balș", Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
National Institute of Research and Development for Biological Sciences · ROCarol Davila University of Medicine and Pharmacy · ROInstitutul Cantacuzino · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza continues to drive seasonal morbidity, particularly in settings with low vaccine coverage.

objectivesTo describe the influenza cases and viral circulation among hospitalized patients.

methodsA prospective study based on active surveillance of inpatients with influenza-like illness from a tertiary hospital in Bucharest, Romania, in the season 2016/17.

resultsA total of 446 patients were tested, with a balanced gender distribution. Overall, 192 (43%) patients tested positive for influenza, with the highest positivity rate in the age groups 3-13 years and >65 years. Peak activity occurred between weeks 1 and 16/2017, with biphasic distribution: A viruses were replaced by B viruses from week 9/2017; B viruses predominated (66.1%). Among the 133 (69.3%) subtyped samples, all influenza A were subtype H3 (n=57) and all influenza B were B/Victoria (n=76). Patients who tested positive for influenza presented fewer comorbidities (p=0.012), except for the elderly, in whom influenza was more common in patients with comorbidities (p=0.050). Disease evolution was generally favorable under antiviral treatment. The length of hospital stay was slightly longer in patients with influenza-like illness who tested patients negative for influenza (p=0.031).

conclusionsDistinctive co-circulation of A/H3 and B/Victoria in Bucharest, Romania in the 2016/17 influenza season was found. While the A/H3 subtype was predominant throughout Europe that season, B/Victoria appears to have circulated specifically in Romania and the Eastern European region, predominantly affecting preschoolers and school children.

Indexed as

Epidemiological MonitoringSeasonsAdolescentAdultAgedAge DistributionChildChild, PreschoolComorbidityFemaleHumansInfantInfluenza A virusInfluenza B virusInfluenza, HumanMaleA/H3B/VictoriaILIInfluenzaSARISubtype

Identifiers

PMID30391275
PMCPMC9427989
OpenAlexW2899434290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.