Evidence map›Paper›PMID 30391249›Full record

ArticleThe Annals of thoracic surgery2019

Sustainability of Infant Cardiac Surgery Early Extubation Practices After Implementation and Study.

Michael Gaies, Sara K Pasquali, Susan C Nicolson, Lara Shekerdemian, Madolin Witte, Michael Wolf, Wenying Zhang, Janet E Donohue, William T Mahle, Pediatric Heart Network Investigators

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Article in The Annals of thoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Early extubation after pediatric cardiac surgery.Anesthesia and pain medicine · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Michael GaiesDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address: mgaies@med.umich.edu.
Sara K PasqualiDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan.
Susan C NicolsonDepartment of Anesthesiology and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.
Lara ShekerdemianDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas.
Madolin WitteDepartment of Pediatrics, University of Utah School of Medicine, Salt Lake City, Utah.
Michael WolfDepartment of Pediatrics, Emory University, Atlanta, Georgia; Sibley Heart Center, Emory University, Atlanta, Georgia.
Wenying ZhangMichigan Congenital Heart Outcomes Research and Discovery Unit, Pediatric Cardiac Critical Care Consortium Data Coordinating Center, University of Michigan, Ann Arbor, Michigan.
Janet E DonohueMichigan Congenital Heart Outcomes Research and Discovery Unit, Pediatric Cardiac Critical Care Consortium Data Coordinating Center, University of Michigan, Ann Arbor, Michigan.
William T MahleDepartment of Pediatrics, Emory University, Atlanta, Georgia; Sibley Heart Center, Emory University, Atlanta, Georgia.
Pediatric Heart Network Investigators
University of Michigan–Ann Arbor · USEmory University · USBaylor College of Medicine · USMichigan Cancer Research Consortium · USUniversity of Pennsylvania · USUniversity of Utah · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Pediatric Heart network DCCU10HL068270 · NHLBI · NEW ENGLAND RESEARCH INSTITUTES, INC. · PI MILLER, JULIE ELAINE, TRACHTENBERG, FELICIA LYNN · 2011 to 2016
$44.9M
Explaining Variation in Mortality after Pediatric Cardiac SurgeryK08HL116639 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAIES, MICHAEL · 2014 to 2018
$767k
NCATS NIH HHS UL1 TR002240NHLBI NIH HHS K08 HL116639NHLBI NIH HHS U10 HL068270
6 · The paper itself

Abstract

backgroundThe Pediatric Heart Network Collaborative Learning Study (PHN CLS) successfully changed practice at four hospitals to increase the rate of early extubation within 6 hours after infant heart surgery. It is unknown whether this practice continued after study completion.

methodsWe linked the PHN CLS dataset to the Pediatric Cardiac Critical Care Consortium registry to compare outcomes at four active hospitals between the study period (post-clinical practice guideline [CPG]) and the first year after study completion (follow-up) after a 3-month washout. Inclusion and exclusion criteria were the same across eras. Primary outcome was early extubation rate after tetralogy of Fallot or aortic coarctation repair. Secondary outcomes included time to first extubation and intensive care and hospital lengths of stay.

resultsThere were 121 patients in the post-CPG era and 139 patients in the follow-up era with no difference in patient characteristics or operation subtypes. Post-CPG early extubation rate declined from 67% to 30% in follow-up (p < 0.0001); time to first extubation increased (4.5 versus 13.5 hours, p < 0.0001). One hospital maintained the rate of early extubation (72% versus 67%), whereas the other three hospitals had significantly lower rates in follow-up (p < 0.02 for each). Intensive care (2.8 versus 2.9 days) and postoperative hospital (6 versus 5 days) stays did not differ between eras (p > 0.05 for both). Findings were consistent across operation subtypes.

conclusionsExtubation practice in the first year of follow-up after the PHN CLS reverted toward prestudy levels. One of four hospitals maintained its early extubation strategy, suggesting that specific implementation and maintenance approaches may effectively sustain impact from quality initiatives.

Indexed as

Airway ExtubationCardiac Surgical ProceduresPractice Patterns, Physicians'Aortic CoarctationClinical ProtocolsFemaleFollow-Up StudiesGuideline AdherenceHumansInfantInfant, NewbornLength of StayMalePostoperative CareTetralogy of FallotTime Factors

Identifiers

PMID30391249
OpenAlexW2899020681

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.