ArticleInternational journal for parasitology2019
Analysis of the Babesia microti proteome in infected red blood cells by a combination of nanotechnology and mass spectrometry.
Article in International journal for parasitology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Acquired motility ofProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Urinary bacteriophage cooperation with bacterial pathogens during human urinary tract infections supports lysogenic phage therapy.Communications biology · 2025Article
- A set of diagnostic tests for detection of active Babesia duncani infection.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2024Article
- Proteomics identification of overexpressed serum proteins in dogs withVeterinary world · 2023Article
- Advances inPathogens (Basel, Switzerland) · 2023Review
- HarnessingVaccines · 2022Review
- In Silico Survey and Characterization ofPathogens (Basel, Switzerland) · 2021Article
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- Evaluation of pathogen specific urinary peptides in tick-borne illnesses.Scientific reports · 2020Article
- Phosphoglycerate kinase: structural aspects and functions, with special emphasis on the enzyme from Kinetoplastea.Open biology · 2020Review
- Proteomic analysis reveals pathogen-derived biomarkers of acute babesiosis in erythrocytes, plasma, and urine of infected hamsters.Parasitology research · 2020Article
- Article
- Persistence ofPathogens (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Proteomics of Babesia microti has lagged behind other apicomplexans despite recent genome and transcriptome studies. Here, we used a combination of nanotechnology and mass spectrometry to provide a proteomic profile of B. microti acute infection. We identified ∼500 parasite proteins in blood with functions such as transport, carbohydrate and energy metabolism, proteolysis, DNA and RNA metabolism, signaling, translation, lipid biosynthesis, and motility and invasion. We also identified surface antigens with roles in the immune response to the parasite. This first evaluation of the B. microti proteome in erythrocytes provides information for the study of intracellular survival and development of diagnostic tools using mass spectrometry.
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Registered trials
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