ReviewTrends in neurosciences2019
Molecular Mechanisms of the Memory Trace.
Review in Trends in neurosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of transcranial magnetic stimulation on spatial memory: a systematic review across animal and human studies.Frontiers in behavioral neuroscience · 2026Pooled it
- Small molecule orexin agonist ROXA-47 enhances learning and memory in mice.Pharmacology, biochemistry, and behavior · 2026Article
- Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Epineuronal space: an emerging hidden hierarchy bridges neuron and mind space.Cell & bioscience · 2026Review
- On the molecular basis of enduring memory in neurons, and cell fate in fibroblasts.Nucleic acids research · 2026Review
- Reductionism in Engram Neuroscience.The European journal of neuroscience · 2026Review
- Dentate Gyrus Engrams in Fear and Reward: Mechanistic Principles, Critical Gaps, and Paths to Translation.Journal of neurochemistry · 2026Review
- Review
- Remembering the opponent: neuronal activation associated with social memory in zebrafish.Frontiers in veterinary science · 2026Article
- Transcriptomic signatures of hippocampal active place avoidance memory maintenance.Frontiers in cellular neuroscience · 2026Article
- HDAC6 Inhibition Drives Synaptic Protein Acetylation and Enhances Long-Term Memory in Mice.Molecular neurobiology · 2025Article
- Proteomics revealed the underlying mechanism of STAT1-induced cognitive deficits in 2-month-old C57 mice.Experimental brain research · 2025Article
- Memory under siege: the cognitive costs of smoking and vaping.Brain, behavior, & immunity - health · 2025Review
- Combinative Protein Expression of Immediate Early Genes c-Fos, Arc, and Npas4 Along Aversive and Appetitive Experience-Related Neural Networks.Hippocampus · 2025Article
- Age and sex independently influence safety learning in mice.Behavioural brain research · 2025Article
- Neuroplasticity and Nervous System Recovery: Cellular Mechanisms, Therapeutic Advances, and Future Prospects.Brain sciences · 2025Review
- Cell-Type Specific Circuits in the Mammillary Body for Place and Object Recognition Memory.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning.Nature communications · 2025Article
- Epigenetics in Learning and Memory.Sub-cellular biochemistry · 2025Review
- Multi-region processing during sleep for memory and cognition.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2025Review
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Over the past half-century, we have gained significant insights into the molecular biology of long-term memory storage at the level of the synapse. In recent years, our understanding of the cellular architecture supporting long-term memory traces has also substantially improved. However, the molecular biology of consolidation at the level of neuronal systems has been relatively neglected. In this opinion article, we first examine our current understanding of the cellular mechanisms of synaptic consolidation. We then outline areas requiring further investigation on how cellular changes contribute to systems consolidation. Finally, we highlight recent findings on the cellular architecture of memory traces in rodents and how the application of new technologies will expand our understanding of systems consolidation at the neural circuit level. In the coming years, this research focus will be critical for understanding the evolution of long-term memories and for enabling the development of novel therapeutics which embrace the dynamic nature of memories.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.