ReviewProgress in brain research2018
Corticospinal excitability during fatiguing whole body exercise.
Review in Progress in brain research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Determining the cortical, corticospinal, and reticulospinal responses to metronome-paced and self-paced strength training.European journal of applied physiology · 2026Trial
- Fatigability of the knee extensors following high- and low-load resistance exercise sessions in trained men.European journal of applied physiology · 2022Trial
- Trial
- Increased corticospinal excitability after rest with short term motor performance.Experimental physiology · 2026Article
- Corticospinal, reticulospinal and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors.Experimental physiology · 2026Article
- Directional Asymmetry of Crossover Neuromuscular Fatigue Following Unilateral Handgrip Exercise in Adults and Prepubertal Children.Medicina (Kaunas, Lithuania) · 2026Article
- On the role of descending drive and group III/IV muscle afferent feedback in modulating corticomotoneuronal excitability during knee-extensor exercise.The Journal of physiology · 2026Article
- Dynamics of brain-muscle interaction with neuromuscular fatigability: systematic review.Frontiers in physiology · 2026Review
- Influence of Talocrural Joint Position on the Quadriceps Femoris Muscle Torque Measured with an Isokinetic and EasyForceJournal of functional morphology and kinesiology · 2025Article
- The Effect of Transcranial Direct Current Stimulation on Basketball Performance-A Scoping Review.Journal of clinical medicine · 2025Review
- Relating cortical morphology, corticospinal excitability, corticomotor representation, and quadriceps strength after anterior cruciate ligament injury.Experimental brain research · 2025Article
- Exploring the Effects of Sleep Deprivation on Physical Performance: An EEG Study in the Context of High-Intensity Endurance.Sports medicine - open · 2025Article
- A novel cortical biomarker signature predicts individual pain sensitivity.medRxiv : the preprint server for health sciences · 2024Article
- Shaping corticospinal pathways in virtual reality: effects of task complexity and sensory feedback during mirror therapy in neurologically intact individuals.Journal of neuroengineering and rehabilitation · 2024Article
- Consuming Beetroot Juice Improves Slalom Performance and Reduces Muscle Soreness in Alpine Skiers under Hypoxic Conditions.Current developments in nutrition · 2024Article
- Effects of Tempo-Controlled Resistance Training on Corticospinal Tract Plasticity in Healthy Controls: A Systematic Review.Healthcare (Basel, Switzerland) · 2024Review
- Rating of Perceived Exertion: A Large Cross-Sectional Study Defining Intensity Levels for Individual Physical Activity Recommendations.Sports medicine - open · 2024Article
- Exacerbated central fatigue and reduced exercise capacity in early-stage breast cancer patients treated with chemotherapy.European journal of applied physiology · 2023Article
- Decoding firings of a large population of human motor units from high-density surface electromyogram in response to transcranial magnetic stimulation.The Journal of physiology · 2023Article
- Critical considerations of the contribution of the corticomotoneuronal pathway to central fatigue.The Journal of physiology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The corticospinal pathway is considered the primary conduit for voluntary motor control in humans. The efficacy of the corticospinal pathway to relay neural signals from higher brain areas to the locomotor muscle, i.e., corticospinal excitability, is subject to alterations during exercise. While the integrity of this motor pathway has historically been examined during single-joint contractions, a small number of investigations have recently focused on whole body exercise, such as cycling or rowing. Although differences in methodologies employed between these studies complicate the interpretation of the existing literature, it appears that the net excitability of the corticospinal pathway remains unaltered during fatiguing whole body exercise. Importantly, this lack of an apparent effect does not designate the absence of change, but a counterbalance of excitatory and inhibitory influences on the two components of the corticospinal pathway, namely the motor cortex and the spinal motoneurons. Specific emphasis is put on group III/IV afferent feedback from locomotor muscle which has been suggested to play a significant role in mediating these changes. Overall, this review aims at summarizing our limited understanding of how fatiguing whole body exercise influences the corticospinal pathway.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.