Evidence map›Paper›PMID 30390631›Full record

ArticleBMC neurology2018

Low self-reported sports activity before stroke predicts poor one-year-functional outcome after first-ever ischemic stroke in a population-based stroke register.

Christian Urbanek, Viola Gokel, Anton Safer, Heiko Becher, Armin J Grau, Florian Buggle, Frederick Palm

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Christian UrbanekDepartment of Neurology, University of Heidelberg, Städtisches Klinikum Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen, Germany. christian_urbanek@hotmail.de.
Viola GokelUniversity of Mannheim, Department of Dermatology, Theodor-Kutzer-Ufer 1-3, Mannheim, 68167, Germany.
Anton SaferUniversity of Heidelberg, Institute of Public Health, Im Neuenheimer Feld 324, Heidelberg, Germany.
Heiko BecherInstitute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Armin J GrauDepartment of Neurology, University of Heidelberg, Städtisches Klinikum Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen, Germany.
Florian BuggleDepartment of Neurology, University of Heidelberg, Städtisches Klinikum Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen, Germany.
Frederick PalmDepartment of Neurology, University of Heidelberg, Städtisches Klinikum Ludwigshafen am Rhein, Bremserstr. 79, 67063, Ludwigshafen, Germany.
Heidelberg University · DEKlinikum Ludwigshafen · DEUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Mannheim · DE

Funding

Deutsche Forschungsgemeinschaft GR1102/6-1
6 · The paper itself

Abstract

backgroundPhysical activity (PA) is associated with lower risk of stroke. We tested the hypothesis that lack of pre-stroke PA is an independent predictor of poor outcome after first-ever ischemic stroke.

methodsWe assessed recent self-reported PA and other potential predictors for loss of functional independence - modified Rankin Scale (mRS) > 2 - one year after first-ever ischemic stroke in 1370 patients registered between 2006 and 2010 in the Ludwigshafen Stroke Study, a population-based stroke registry.

resultsAfter 1 year, 717 (52.3%) of patients lost their independence including 251 patients (18.3%) who had died. In multivariate logistic regression analysis lack of regular PA prior to stroke (Odds Ratio (OR) 1.7, Confidence Interval (CI) 1.1-2.5), independently predicted poor outcome together with higher age (65-74: OR 1.7; CI 1.1-2.8, 75-84 years: OR 3.3; CI 2.1-5.3; ≥85 years OR 14.5; CI 7.4-28.5), female sex (OR 1.5; CI 1.1-2.1), diabetes mellitus (OR 1.8; CI 1.3-2.5), stroke severity (OR 1.2; CI 1.1-1.2), probable atherothrombotic stroke etiology (OR 1.8; CI 1.1-2.8) and high leukocyte count (> 9.000/mm

conclusionIn addition to previously reported factors, lack of PA prior to stroke as potential indicator of worse physical condition, high leukocyte count at admission as indicator of the inflammatory response and probable atherothrombotic stroke etiology might be independent predictors for non-functional independence in first-ever ischemic stroke.

Indexed as

AgedAge FactorsBrain IschemiaFemaleGermanyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioRegistriesSelf ReportSex FactorsSportsStrokeCerebral infarctionOutcomePhysical activityPredictorsRisk factorsStroke

Identifiers

PMID30390631
PMCPMC6215339
OpenAlexW2899215503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.