Evidence map›Paper›PMID 30390422›Full record

ArticleCell calcium2018

STIM1 R304W causes muscle degeneration and impaired platelet activation in mice.

Thilini H Gamage, Gjermund Gunnes, Robert Hugh Lee, William Edward Louch, Asbjørn Holmgren, Joseph D Bruton, Emma Lengle, Terje R Selnes Kolstad, Tobias Revold, Silja Svanstrøm Amundsen and 9 more

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. The CaBiomolecules · 2023
    Review
  7. Review
  8. Article
  9. Silencing of the CaInternational journal of molecular sciences · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Store-Operated Calcium Entry in the Cardiovascular System.Advances in experimental medicine and biology · 2021
    Review
  14. Article
  15. Frontiers in physiology · 2020
    Review
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 3 countries.

Thilini H GamageDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Gjermund GunnesFaculty of Veterinary Medicine, Norwegian University of Life Sciences, Norway.
Robert Hugh LeeDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, USA.
William Edward LouchInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo Norway.
Asbjørn HolmgrenDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Joseph D BrutonDepartment of Physiology and Pharmacology, Karolinska Institute, 171 77 Stockholm, Sweden.
Emma LengleDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Terje R Selnes KolstadInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo Norway.
Tobias RevoldFaculty of Veterinary Medicine, Norwegian University of Life Sciences, Norway.
Silja Svanstrøm AmundsenDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Knut Tomas DalenNorwegian Transgenic Center, University of Oslo, Oslo, Norway.
Pål Andre HolmeDepartment of Haematology, Oslo University Hospital, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Geir Erland TjønnfjordDepartment of Haematology, Oslo University Hospital, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Geir ChristensenInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo Norway.
Håkan WesterbladDepartment of Physiology and Pharmacology, Karolinska Institute, 171 77 Stockholm, Sweden.
Arne KlunglandDepartment of Molecular Medicine, Oslo University Hospital, Norway.
Wolfgang BergmeierDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, USA.
Doriana MisceoDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.
Eirik FrengenDepartment of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway. Electronic address: eirik.frengen@medisin.uio.no.
Oslo University Hospital · NOKarolinska Institutet · SENorwegian University of Life Sciences · NOUniversity of North Carolina at Chapel Hill · USUniversity of Oslo · NO

Funding

Research Training in Hematology at UNC Chapel HillT32HL007149 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Nigel S. Key · 1985 to 2026
$8.6M
Rap1 signaling in platelet homeostasis and vascular hemostasisR01HL130404 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERGMEIER, WOLFGANG · 2016 to 2018
$1.2M
NHLBI NIH HHS R01 HL130404NHLBI NIH HHS T32 HL007149
6 · The paper itself

Abstract

STIM1 and ORAI1 regulate store-operated Ca

Indexed as

Platelet ActivationAnimalsCalciumFemaleLocomotionMaleMiceMice, Inbred StrainsMuscle, SkeletalStromal Interaction Molecule 1CalciumStim1 protein, mouseStromal Interaction Molecule 1Muscle degenerationPlatelet dysfunctionStim1 expressionStim1 R304WStormorken syndrome

Identifiers

PMID30390422
PMCPMC6481308
OpenAlexW2895348205

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.