ArticleBrain structure & function2019
Associations of age and sex with brain volumes and asymmetry in 2-5-week-old infants.
Article in Brain structure & function, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 72 citations in OpenAlex.
- Massage-Related Changes in Cortical Activity and Cerebral Oxygenation in Healthy Term Infants: An Exploratory EEG-fNIRS Study with Sex-Specific Observations.Neurology international · 2026Article
- SEPoolConvNeXt: A Deep Learning Framework for Automated Classification of Neonatal Brain Development Using T1- and T2-Weighted MRI.Journal of clinical medicine · 2025Article
- The FinnBrain multimodal neonatal template and atlas collection.Communications biology · 2025Article
- Establishing group-level brain structural connectivity incorporating anatomical knowledge under latent space modeling.Medical image analysis · 2025Article
- Axial and mean diffusivity predict myelin density in the hippocampus of pigs during early brain development, independent of sex.Frontiers in neuroscience · 2025Article
- First establishment of population-specific brain volume reference standards for Chinese children and adolescents: an AI-based segmentation study.Frontiers in pediatrics · 2025Article
- Brain volume in infants with metopic synostosis: Less white matter volume with an accelerated growth pattern in early life.Journal of anatomy · 2024Article
- Sex Differences in Human Brain Structure at Birth.Biology of sex differences · 2024Article
- Characterizing normal perinatal development of the human brain structural connectivity.Human brain mapping · 2024Article
- Large-scale analysis of structural brain asymmetries during neurodevelopment: Associations with age and sex in 4265 children and adolescents.Human brain mapping · 2024Article
- Determination of Novel, Cranium-Based Relationships for Construct Placement in Microtia Reconstruction for Hemifacial Microsomia Patients.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024Article
- Associations between maternal pre-pregnancy BMI and infant striatal mean diffusivity.BMC medicine · 2024Article
- Can Brain Volume-Driven Characteristic Features Predict the Response of Alzheimer's Patients to Repetitive Transcranial Magnetic Stimulation? A Pilot Study.Brain sciences · 2024Article
- Brain asymmetry is globally different in males and females: exploring cortical volume, area, thickness, and mean curvature.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Associations between mother's depressive symptoms during pregnancy and newborn's brain functional connectivity.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Ultrasonographic evaluation of the early brain growth pattern in very low birth weight infants.Pediatric research · 2023Article
- Sex differences in brain volumes and psychological distress: The first hundred brains cohort of the longitudinal adolescent brain study.Neuroimage. Reports · 2023Article
- Association of Preterm Birth and Socioeconomic Status With Neonatal Brain Structure.JAMA network open · 2023Article
- Characterization of dynamic patterns of human fetal to neonatal brain asymmetry with deformation-based morphometry.Frontiers in neuroscience · 2023Article
- Prenatal and early-life environmental factors, family demographics and cortical brain anatomy in 5-year-olds: an MRI study from FinnBrain Birth Cohort.Brain imaging and behavior · 2022Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Information on normal brain structure and development facilitates the recognition of abnormal developmental trajectories and thus needs to be studied in more detail. We imaged 68 healthy infants aged 2-5 weeks with high-resolution structural MRI (magnetic resonance imaging) and investigated hemispheric asymmetry as well as the associations of various total and lobar brain volumes with infant age and sex. We found similar hemispheric asymmetry in both sexes, seen as larger volumes of the right temporal lobe, and of the left parietal and occipital lobes. The degree of asymmetry did not vary with age. Regardless of controlling for gestational age, gray and white matter had different age-related growth patterns. This is a reflection of gray matter growth being greater in the first years, while white matter growth extends into early adulthood. Sex-dependent differences were seen in gray matter as larger regional absolute volumes in males and as larger regional relative volumes in females. Our results are in line with previous studies and expand our understanding of infant brain development.
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