Evidence map›Paper›PMID 30389854›Full record

ArticleDevelopment (Cambridge, England)2018

WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development.

Akiko Suzuki, Ryohei Minamide, Junichi Iwata

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Akiko SuzukiDepartment of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston (UT Health) School of Dentistry, Houston, TX 77054, USA.ORCID 0000-0003-3163-8093
Ryohei MinamideDepartment of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston (UT Health) School of Dentistry, Houston, TX 77054, USA.ORCID 0000-0001-8708-366X
Junichi IwataDepartment of Diagnostic and Biomedical Sciences, The University of Texas Health Science Center at Houston (UT Health) School of Dentistry, Houston, TX 77054, USA junichi.iwata@uth.tmc.edu.ORCID 0000-0003-3975-6836
International Craniofacial Institute · USThe University of Texas MD Anderson Cancer Center · US

Funding

Molecular Regulatory Mechanism of Calvaria Bone Development and HomeostasisR01DE026767 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2017 to 2021
$1.8M
Transcripts and Functions Targeted by Non-coding RNAs in Palate DevelopmentR03DE026208 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2016 to 2017
$462k
Identification of microRNAs associated with cleft lipR03DE026509 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2017 to 2018
$462k
Role of WNT Signaling in Craniofacial Muscle DevelopmentR03DE024759 · NIDCR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI IWATA, JUNICHI · 2015 to 2016
$231k
NIDCR NIH HHS R01 DE026767NIDCR NIH HHS R03 DE024759NIDCR NIH HHS R03 DE026208NIDCR NIH HHS R03 DE026509
6 · The paper itself

Abstract

Skeletal muscle development is controlled by a series of multiple orchestrated regulatory pathways. WNT/β-catenin is one of the most important pathways for myogenesis; however, it remains unclear how this signaling pathway regulates myogenesis in a temporal- and spatial-specific manner. Here, we show that WNT/β-catenin signaling is crucial for myoblast fusion through regulation of the nephrin (

Indexed as

Muscle DevelopmentWnt Signaling PathwayAnimalsCell DifferentiationCell FusionCell LineageMembrane ProteinsMiceMyoblastsTongueMembrane ProteinsnephrinMuscle developmentMyoblast fusionNephrinWNT/β-catenin signaling

Identifiers

PMID30389854
PMCPMC6288386
OpenAlexW2898647755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.