Evidence map›Paper›PMID 30389796›Full record

ArticleG3 (Bethesda, Md.)2019

Fitness and Genomic Consequences of Chronic Exposure to Low Levels of Copper and Nickel in

James K Bull, Jullien M Flynn, Frederic J J Chain, Melania E Cristescu

Abstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Fitness effects of spontaneous mutations in a warming world.Evolution; international journal of organic evolution · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

James K BullDepartment of Biology, McGill University, Quebec, Canada, H3A 1B1 james.bull.au@gmail.com.ORCID 0000-0002-0274-4359
Jullien M FlynnMolecular Biology and Genetics, Cornell University, New York, 14853.
Frederic J J ChainDepartment of Biological Sciences, University of Massachusetts, Lowell, Massachusetts, 01854.
Melania E CristescuDepartment of Biology, McGill University, Quebec, Canada, H3A 1B1.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In at least some unicellular organisms, mutation rates are temporarily raised upon exposure to environmental stress, potentially contributing to the evolutionary response to stress. Whether this is true for multicellular organisms, however, has received little attention. This study investigated the effects of chronic mild stress, in the form of low-level copper and nickel exposure, on mutational processes in

Indexed as

AnimalsCopperDaphniaGenetic FitnessGenomeMutationMutation AccumulationMutation RateNickelReproductionSequence DeletionCopperNickelgenetic loadlife-history evolutionmetal pollutionmutational decaymutation rate

Identifiers

PMID30389796
PMCPMC6325897

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.