Evidence map›Paper›PMID 30389788›Full record

ArticleThe Journal of biological chemistry2018

The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosis.

Shuai Hu, Runhong Han, Jingsong Shi, Xiaodong Zhu, Weisong Qin, Caihong Zeng, Hao Bao, Zhihong Liu

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. MicroRNAs in kidney injury and disease.Nature reviews. Nephrology · 2022
    Review
  16. Article
  17. Article
  18. Article
  19. The Zebrafish Model to Understand Epigenetics in Renal Diseases.International journal of molecular sciences · 2021
    Review
  20. Non-Coding RNAs in Kidney Diseases: The Long and Short of Them.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Shuai HuFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and.
Runhong HanFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and; the School of Medicine, Southeast University, Nanjing 210009, China.
Jingsong ShiFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and.
Xiaodong ZhuFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and.
Weisong QinFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and.
Caihong ZengFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and.
Hao BaoFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and. Electronic address: bhao@nju.edu.cn.
Zhihong LiuFrom the National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002 and. Electronic address: zhihong-liu@hotmail.com.
Nanjing General Hospital of Nanjing Military Command · CNNational Clinical Research · USNanjing University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focal segmental glomerulosclerosis (FSGS) is a common kidney disease that results in nephrotic syndrome. FSGS arises from dysfunction and apoptosis of podocytes in the glomerulus of the kidney, leading to podocytopathy. The molecular mechanisms underlying podocyte apoptosis remain incompletely understood. Using an array of gene expression profiling, PCR, and

Indexed as

bcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCCAAT-Enhancer-Binding Protein-betaCells, CulturedDoxorubicinFemaleGene Expression RegulationGlomerulosclerosis, Focal SegmentalHumansMaleMicroRNAsPodocytesRNA, Long NoncodingSignal TransductionBAK1 protein, humanBAX protein, humanbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCCAAT-Enhancer-Binding Protein-betaCEBPB protein, humanDoxorubicinMicroRNAsRNA, Long Noncodingapoptosisfocal segmental glomerulosclerosiskidney diseaselong noncoding RNA (long ncRNA, lncRNA)microRNA (miRNA)nephrologynephrotic syndromepodocyteposttranscriptional regulation

Identifiers

PMID30389788
PMCPMC6311495
OpenAlexW2899198422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.