Evidence map›Paper›PMID 30389666›Full record

ArticleThe EMBO journal2018

Stress-induced host membrane remodeling protects from infection by non-motile bacterial pathogens.

Caroline Tawk, Giulia Nigro, Ines Rodrigues Lopes, Carmen Aguilar, Clivia Lisowski, Miguel Mano, Philippe Sansonetti, Jörg Vogel, Ana Eulalio

Open access · hybridAbstract read
In one paragraph

Article in The EMBO journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Current prevalence and therapeutic strategies for porcineApplied and environmental microbiology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Acid Sphingomyelinase Deficiency: A Clinical and Immunological Perspective.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Caroline TawkHost RNA Metabolism Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.ORCID 0000-0003-1781-5591
Giulia NigroMolecular Microbial Pathogenesis Laboratory, Institut Pasteur, Paris, France.
Ines Rodrigues LopesFunctional Genomics and RNA-based Therapeutics, UC-BIOTECH, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.
Carmen AguilarHost RNA Metabolism Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.
Clivia LisowskiHost RNA Metabolism Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.
Miguel ManoFunctional Genomics and RNA-based Therapeutics, UC-BIOTECH, Center for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.ORCID 0000-0003-1922-4824
Philippe SansonettiMolecular Microbial Pathogenesis Laboratory, Institut Pasteur, Paris, France.ORCID 0000-0001-7542-4527
Jörg VogelRNA Biology Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany.ORCID 0000-0003-2220-1404
Ana EulalioHost RNA Metabolism Group, Institute for Molecular Infection Biology (IMIB), University of Würzburg, Würzburg, Germany ana.eulalio@uni-wuerzburg.de aeulalio@ci.uc.pt.ORCID 0000-0002-7355-0674
University of Würzburg · DEInstitut Pasteur · FRUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While mucosal inflammation is a major source of stress during enteropathogen infection, it remains to be fully elucidated how the host benefits from this environment to clear the pathogen. Here, we show that host stress induced by different stimuli mimicking inflammatory conditions strongly reduces the binding of

Indexed as

Immunity, InnateAnimalsCell MembraneDysentery, BacillaryEpithelial CellsGuinea PigsSalmonella InfectionsSalmonella typhimuriumShigella flexneriStress, Physiologicalacid sphingomyelinasehost stress responsemembrane remodelingSalmonellaShigella

Identifiers

PMID30389666
PMCPMC6276891
OpenAlexW2898614601

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.