Evidence map›Paper›PMID 30389646›Full record

ArticleJMIR mHealth and uHealth2018

Implementation Tells Us More Beyond Pooled Estimates: Secondary Analysis of a Multicountry mHealth Trial to Reduce Blood Pressure.

Rodrigo M Carrillo-Larco, Safia S Jiwani, Francisco Diez-Canseco, Rebecca Kanter, Andrea Beratarrechea, Vilma Irazola, Manuel Ramirez-Zea, Adolfo Rubinstein, Homero Martinez, J Jaime Miranda and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in JMIR mHealth and uHealth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01295216 (Mobile Health to Prevent Progression of Pre-hypertension in Latin American Urban Settings), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01295216 naterminatednot on this map

Mobile Health to Prevent Progression of Pre-hypertension in Latin American Urban Settings

TypeinterventionalSponsorInstitute of Nutrition of Central America and PanamaRan2011 to 2013Enrolled637ConditionsHypertension, PrehypertensionArmsMobile technology to promote lifestyle modification
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rodrigo M Carrillo-LarcoCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-2090-1856
Safia S JiwaniCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-9896-8858
Francisco Diez-CansecoCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-7611-8190
Rebecca KanterINCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala, Guatemala.ORCID http://orcid.org/0000-0003-4867-5448
Andrea BeratarrecheaSouth American Center of Excellence for Cardiovascular Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-6397-4406
Vilma IrazolaSouth American Center of Excellence for Cardiovascular Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-6100-1862
Manuel Ramirez-ZeaINCAP Research Center for the Prevention of Chronic Diseases, Institute of Nutrition of Central America and Panama, Guatemala, Guatemala.ORCID http://orcid.org/0000-0001-5107-9175
Adolfo RubinsteinSouth American Center of Excellence for Cardiovascular Health, Institute for Clinical Effectiveness and Health Policy, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-8418-6134
Homero MartinezNutrition International, Ottawa, ON, Canada.ORCID http://orcid.org/0000-0002-1435-0306
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.ORCID http://orcid.org/0000-0002-4738-5468
GISMAL GroupCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru.

Funding

NHLBI NIH HHS HHSN268200900028C
6 · The paper itself

Abstract

backgroundThe uptake of an intervention aimed at improving health-related lifestyles may be influenced by the participant's stage of readiness to change behaviors.

objectiveWe conducted secondary analysis of the Grupo de Investigación en Salud Móvil en América Latina (GISMAL) trial according to levels of uptake of intervention (dose-response) to explore outcomes by country, in order to verify the consistency of the trial's pooled results, and by each participant's stage of readiness to change a given lifestyle at baseline. The rationale for this secondary analysis is motivated by the original design of the GISMAL study that was independently powered for the primary outcome-blood pressure-for each country.

methodsWe conducted a secondary analysis of a mobile health (mHealth) multicountry trial conducted in Argentina, Guatemala, and Peru. The intervention consisted of monthly motivational phone calls by a trained nutritionist and weekly tailored text messages (short message service), over a 12-month period, aimed to enact change on 4 health-related behaviors: salt added to foods when cooking, consumption of high-fat and high-sugar foods, consumption of fruits or vegetables, and practice of physical activity. Results were stratified by country and by participants' stage of readiness to change (precontemplation or contemplation; preparation or action; or maintenance) at baseline. Exposure (intervention uptake) was the level of intervention (<50%, 50%-74%, and ≥75%) received by the participant in terms of phone calls. Linear regressions were performed to model the outcomes of interest, presented as standardized mean values of the following: blood pressure, body weight, body mass index, waist circumference, physical activity, and the 4 health-related behaviors.

resultsFor each outcome of interest, considering the intervention uptake, the magnitude and direction of the intervention effect differed by country and by participants' stage of readiness to change at baseline. Among those in the high intervention uptake category, reductions in systolic blood pressure were only achieved in Peru, whereas fruit and vegetable consumption also showed reductions among those who were at the maintenance stage at baseline in Argentina and Guatemala.

conclusionsDesigning interventions oriented toward improving health-related lifestyle behaviors may benefit from recognizing baseline readiness to change and issues in implementation uptake.

trial registrationClinicalTrials.gov NCT01295216; http://clinicaltrials.gov/ct2/show/NCT01295216 (Archived by WebCite at http://www.webcitation.org/72tMF0B7B).

Indexed as

Argentinabehaviorclinical trialGuatemalahealth risk behaviors, lifestyle risk reductionmHealthPeru

Identifiers

PMID30389646
PMCPMC6238100

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.