Evidence map›Paper›PMID 30389452›Full record

ArticleRespiratory physiology & neurobiology2019

Influence of propofol on isolated neonatal rat carotid body glomus cell response to hypoxia and hypercapnia.

Peadar B O'Donohoe, Philip J Turner, Nicky Huskens, Keith J Buckler, Jaideep J Pandit

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory physiology & neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Peadar B O'DonohoeDepartment of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK; Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, UK.
Philip J TurnerDepartment of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK.
Nicky HuskensDepartment of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK.
Keith J BucklerDepartment of Physiology, Anatomy & Genetics, Parks Road, University of Oxford, Oxford, OX1 3PT, UK.
Jaideep J PanditNuffield Department of Anaesthetics, Oxford University Hospitals NHS Trust, Oxford, OX3 9DU, UK. Electronic address: jaideep.pandit@dpag.ox.ac.uk.
University of Oxford · GBOxford University Hospitals NHS Trust · GB

Funding

Medical Research Council MR/J011452/1
6 · The paper itself

Abstract

In humans the intravenous anaesthetic propofol depresses ventilatory responses to hypoxia and CO

Indexed as

AnimalsAnimals, NewbornCalciumCarbon DioxideCarotid BodyCell HypoxiaChemoreceptor CellsCholinergic AgentsDose-Response Relationship, DrugDrug InteractionsGABA AgentsHypercapniaHypnotics and SedativesMembrane PotentialsPatch-Clamp TechniquesPotassiumCalciumCarbon DioxideCholinergic AgentsGABA AgentsHypnotics and SedativesPotassiumPropofolCarotid bodyChemosensitivityHypoxiaPropofol

Identifiers

PMID30389452
PMCPMC6336315
OpenAlexW2898737745

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.