ArticleEnvironment international2018
Prenatal lead exposure and elevated blood pressure in children.
Article in Environment international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 57 citations in OpenAlex.
- Environmental Exposures and Atherosclerotic Risk Factors in Vulnerable Youth: The Example of American Indian/Alaska Native Populations.Current atherosclerosis reports · 2026Review
- Time-Varying Exposure to Element Mixtures and Children's Cognition at 5 Years of Age: Findings from the New Hampshire Birth Cohort Study.Environmental health perspectives · 2026Article
- Early-Life Lead Exposure and Male Longevity: Evidence from Historical Municipal Water Systems.Explorations in economic history · 2025Article
- Baseline associations between exposure to metals and systolic and diastolic blood pressure among women in the Household Air Pollution Intervention Network Trial.medRxiv : the preprint server for health sciences · 2025Article
- The Impact of Blood Lead and Its Interaction with Occupational Factors and Air Pollution on Hypertension Prevalence.Toxics · 2024Article
- The Assessment of Anthropometric Measures and Changes in Selected Biochemical Parameters in Obese Children in Relation to Blood Lead Level.Metabolites · 2024Article
- Pilot Monitoring of Lead in Umbilical Cord Blood of Newborns Associated With the Use of Glazed Ceramics from Guanajuato, Mexico.Biological trace element research · 2024Article
- Environmental Exposures and Pediatric Cardiology: A Scientific Statement From the American Heart Association.Circulation · 2024Review
- Periconceptional and Prenatal Exposure to Metals and Extracellular Vesicle and Particle miRNAs in Human Milk: A Pilot Study.Exposure and health · 2023Article
- Metals and per- and polyfluoroalkyl substances mixtures and birth outcomes in the New Hampshire Birth Cohort Study: Beyond single-class mixture approaches.Chemosphere · 2023Article
- Perinatal Lead Exposure Promotes Sex-Specific Epigenetic Programming of Disease-Relevant Pathways in Mouse Heart.Toxics · 2023Article
- The Minderoo-Monaco Commission on Plastics and Human Health.Annals of global health · 2023Review
- Perinatal Metal and Metalloid Exposures and Offspring Cardiovascular Health Risk.Current environmental health reports · 2022Review
- Prenatal lead (Pb) exposure is associated with differential placental DNA methylation and hydroxymethylation in a human population.Epigenetics · 2022Article
- Toxic Metals in Particulate Matter and Health Risks in an E-Waste Dismantling Park and Its Surrounding Areas: Analysis of Three PM Size Groups.International journal of environmental research and public health · 2022Article
- Article
- Developmental toxicant exposures and sex-specific effects on epigenetic programming and cardiovascular health across generations.Environmental epigenetics · 2022Review
- A metabolome-wide association study of in utero metal and trace element exposures with cord blood metabolome profile: Findings from the Boston Birth Cohort.Environment international · 2022Article
- Machine-learning models predicting osteoarthritis associated with the lead blood level.Environmental science and pollution research international · 2021Article
- Blood Lead, Systemic Inflammation, and Blood Pressure: Exploring Associations and Mediation Effects in Workers Exposed to Lead.Biological trace element research · 2021Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Growing evidence suggests that environmental exposures can influence blood pressure over the course of a lifetime. Exposure to toxic metals, such as lead (Pb) and arsenic (As), has been associated with increased blood pressure in adults, but few studies have examined the impacts of in utero and early life toxic metals exposure on blood pressure in childhood. As subclinical vascular changes are thought to begin early in life, it is possible that in utero toxic metals exposure may play a role in blood pressure homeostasis. In the ongoing New Hampshire Birth Cohort Study, we investigated whether in utero exposure to Pb and As was associated with measures of blood pressure in a total of 323 young children (mean age 5.5 years, SD 0.4). Pb and As were measured in maternal toenail samples collected at ~28 weeks gestation (n = 257) and/or 6 weeks postpartum (n = 285), which represent exposures ~6 to 12 months prior to collection and therefore reflect the early prenatal and late prenatal exposures, respectively. Five measurements of systolic blood pressure (SBP) and diastolic blood pressure (DBP) were averaged for each child using a standardized technique. In linear regression analyses, where log
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.