Evidence map›Paper›PMID 30389227›Full record

ReviewSeminars in perinatology2018

Recent advances in antenatal factors predisposing to bronchopulmonary dysplasia.

Elizabeth Taglauer, Steven H Abman, Roberta L Keller

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in perinatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 4 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 4 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Titrating cumulative neonatal hyperoxia in mice to model bronchopulmonary dysplasia severities.American journal of respiratory cell and molecular biology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Mesenchymal stromal cell extracellular vesicles improve lung development in mechanically ventilated preterm lambs.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  17. Article
  18. Article
  19. The Role of Lung Function in Determining Which Children Develop Asthma.The journal of allergy and clinical immunology. In practice · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elizabeth TaglauerHarvard Neonatal-Perinatal Fellowship Program, Boston, MA USA.
Steven H AbmanPediatric Heart Lung Center, Department of Pediatrics, University of Colorado Anschutz School of Medicine, Aurora, CO USA.
Roberta L KellerDivision of Neonatology, Department of Pediatrics, University of California San Francisco, San Francisco, CA USA. Electronic address: Roberta.Keller@ucsf.edu.
University of California, San Francisco · US

Funding

RESPIRATORY RESEARCHT32HL007633 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI George R Washko · 1985 to 2026
$14.9M
Role of VEGF in Perinatal Pulmonary HypertensionR01HL068702 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ABMAN, STEVEN HERBERT, SHEPHERD, DOUGLAS · 2001 to 2021
$6.7M
Genetic Basis for Impaired Angiogenic Signaling in BPDR01HL085703 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ABMAN, STEVEN HERBERT · 2008 to 2012
$3.3M
UCSF Clinical Research Center for Prematurity and Respiratory Outcomes ProgramU01HL101798 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BALLARD, PHILIP L., KELLER, ROBERTA L · 2010 to 2014
$2.1M
NHLBI NIH HHS R01 HL068702NHLBI NIH HHS R01 HL085703NHLBI NIH HHS T32 HL007633NHLBI NIH HHS U01 HL101798
6 · The paper itself

Abstract

Bronchopulmonary dysplasia (BPD) remains a major cause of late morbidities and death after preterm birth. BPD is characterized by an arrest of vascular and alveolar growth and high risk for pulmonary hypertension; yet mechanisms contributing to its pathogenesis and early strategies to prevent BPD are poorly understood. Strong epidemiologic studies have shown that the "new BPD" reflects the long-lasting impact of antenatal factors on lung development, partly due to placental dysfunction, as reflected in recent data from animal models. Improved understanding of mechanisms through which antenatal stress alters placental function and contributes to BPD may lead to preventive therapies.

Indexed as

Amniotic FluidBronchopulmonary DysplasiaCausalityFemaleHumansHypertension, PulmonaryInfant, Extremely PrematureInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightLungOxidative StressPlacenta Growth FactorPregnancyPremature BirthUnited StatesPlacenta Growth FactorVascular Endothelial Growth Factor AVEGFA protein, humanAlveolarizationAngiogenesisPlacentaRespiratory morbidityVascular endothelial growth factor (VEGF)Vasculogenesis

Identifiers

PMID30389227
PMCPMC6286866
OpenAlexW2895104415

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.