Evidence map›Paper›PMID 30389074›Full record

ReviewChild and adolescent psychiatric clinics of North America2019

Transcranial Magnetic Stimulation for Adolescent Depression.

Paul E Croarkin, Frank P MacMaster

Abstract readReview
In one paragraph

Review in Child and adolescent psychiatric clinics of North America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.

  1. Pooled it
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  3. [Efficacy evaluation of repeated transcranial magnetic stimulation combined with bipolar depression triple therapy in reducing female adolescents' non-suicidal self-injury].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Paul E CroarkinChild and Adolescent Psychiatry, Mayo Clinic College of Medicine and Science, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: croarkin.paul@mayo.edu.
Frank P MacMasterStrategic Clinical Network for Addictions and Mental Health, University of Calgary, Alberta Children's Hospital, Office Number: B4-511, 2500 University Dr. NWCalgary, Alberta, T2N 1N4, Canada.
Alberta Children's Hospital · CAMayo Clinic · US

Funding

Glutamatergic and GABAergic Biomarkers in rTMS for Adolescent DepressionR01MH113700 · NIMH · MAYO CLINIC ROCHESTER · PI CROARKIN, PAUL E · 2017 to 2021
$2.5M
NIMH NIH HHS R01 MH113700
6 · The paper itself

Abstract

Adolescent depression is a substantial global public health problem that contributes to academic failure, occupational impairment, deficits in social functioning, substance use disorders, teen pregnancy, and completed suicide. Existing treatment options often have suboptimal results and uncertain safety profiles. Transcranial magnetic stimulation may be a promising, brain-based intervention for adolescents with depression. Existing work has methodological weaknesses, and larger, neurodevelopmentally informed studies are urgently needed. Treatment with transcranial magnetic stimulation may modulate cortical GABAergic and glutamatergic imbalances. Future study will inform dosing approaches for TMS based on GABAergic and glutamatergic biomarkers.

Indexed as

AdolescentAdolescent PsychiatryGlobal HealthHumansMajor Depressive DisorderPublic HealthTranscranial Magnetic StimulationAdolescentBrain stimulationDepressionGABAGlutamateNeuromodulationTMSTranscranial magnetic stimulation

Identifiers

PMID30389074
PMCPMC6221455
OpenAlexW2889282839

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.