Evidence map›Paper›PMID 30388683›Full record

ArticleRedox biology2019

Calcium signals between the ryanodine receptor- and mitochondria critically regulate the effects of arsenite on mitochondrial superoxide formation and on the ensuing survival vs apoptotic signaling.

Andrea Guidarelli, Mara Fiorani, Liana Cerioni, Orazio Cantoni

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Distinct CaArchives of toxicology · 2026
    Article
  3. Review
  4. Co-exposure to arsenic and nickel induces oxidative stress and mineral imbalance, impairing male reproductive parameters in Wistar rats.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Effects of O-GlcNAcylation on functional mitochondrial transfer from astrocytes.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Prostaglandin EFrontiers in pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Andrea GuidarelliDepartment of Biomolecular Sciences, University of Urbino, Carlo Bo, via Saffi 2, 61029 Urbino, PU, Italy.
Mara FioraniDepartment of Biomolecular Sciences, University of Urbino, Carlo Bo, via Saffi 2, 61029 Urbino, PU, Italy.
Liana CerioniDepartment of Biomolecular Sciences, University of Urbino, Carlo Bo, via Saffi 2, 61029 Urbino, PU, Italy.
Orazio CantoniDepartment of Biomolecular Sciences, University of Urbino, Carlo Bo, via Saffi 2, 61029 Urbino, PU, Italy. Electronic address: orazio.cantoni@uniurb.it.
University of Urbino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A low concentration of arsenite (6 h), selectively stimulating the intraluminal crosstalk between the inositol-1, 4, 5-triphosphate receptor and the ryanodine receptor (RyR), increased the mitochondrial transport of RyR-derived Ca

Indexed as

ApoptosisArsenitesBiomarkersCalciumCalcium SignalingCell LineCell SurvivalDNA Breaks, Single-StrandedHumansMembrane Potential, MitochondrialMitochondriaRyanodine Receptor Calcium Release ChannelSignal TransductionSuperoxidesarseniteArsenitesBiomarkersCalciumRyanodine Receptor Calcium Release ChannelSuperoxidesArseniteInositol-1, 4, 5-triphosphate receptorMitochondrial Ca(2+)Mitochondrial superoxideRyanodine receptorSurvival vs apoptotic signaling

Identifiers

PMID30388683
PMCPMC6216081
OpenAlexW2895976215

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.