ArticleCell stem cell2018
Stem-Cell-Derived Astrocytes Divulge Secrets of Mutant GFAP.
Article in Cell stem cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Sbno1 mediates cell-cell communication between neural stem cells and microglia through small extracellular vesicles.Cell & bioscience · 2024Article
- GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria.Frontiers in cell and developmental biology · 2023Article
- When glia meet induced pluripotent stem cells (iPSCs).Molecular and cellular neurosciences · 2020Review
- [Effect of advanced maternal age on development of hippocampal neural stem cells in offspring rats].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer.Frontiers in cellular neuroscience · 2019Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gain-of-function mutations in the canonical astrocyte protein, GFAP, cause a fatal neurodevelopmental disorder with myelination abnormalities, seizures, and psychomotor disturbances. Recently, Li et al. (2018) (in Cell Stem Cell) and Jones et al. (2018) (in Cell Reports) have shown that patient iPSC-derived astrocytes with mutant GFAP have disrupted astrocyte functions, revealing disease mechanisms and potential roles of GFAP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.