Evidence map›Paper›PMID 30388416›Full record

ArticleCell stem cell2018

Epidermal Darwinism and Competitive Equilibrium within the Epidermis.

Mingxing Lei, Cheng-Ming Chuong

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell stem cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Mingxing LeiIntegrative Stem Cell Center, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Institute of New Drug Development, College of Biopharmaceutical and Food Sciences, China Medical University, Taichung 40402, Taiwan.
Cheng-Ming ChuongIntegrative Stem Cell Center, China Medical University Hospital, China Medical University, Taichung 40402, Taiwan; Department of Pathology, University of Southern California, Los Angeles, CA 90033, USA. Electronic address: cmchuong@usc.edu.
China Medical University · TWUniversity of Southern California · US

Funding

Size regulation of skin appendagesR01AR047364 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Cheng-Ming Chuong · 2002 to 2026
$10.1M
Tissue Engineering of New Hair FormationR01AR060306 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHUONG, CHENG-MING · 2010 to 2019
$4.6M
Tissue Patterning in living skin and organ explantsR37AR060306 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Cheng-Ming Chuong · 2020 to 2026
$3.6M
Tissue mechanics in regenerative wound healing of the skinR01GM125322 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHUONG, CHENG-MING · 2018 to 2021
$1.3M
NIAMS NIH HHS R01 AR060306NIAMS NIH HHS R37 AR060306NIGMS NIH HHS R01 GM125322
6 · The paper itself

Abstract

In normal homeostasis, cancer defense, or stem cell therapy, epidermal progenitors undergo constant competition to reach an equilibrium state. In this issue of Cell Stem Cell, Mesa et al. (2018) and Murai et al. (2018) show that skin epidermal progenitors maintain tissue homeostasis through competitive equilibrium under physiological self-renewal or oncogenic conditions.

Indexed as

Cell Self RenewalEpidermisCell DifferentiationHomeostasis

Identifiers

PMID30388416
PMCPMC7428142
OpenAlexW2899174119

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.