Evidence map›Paper›PMID 30388277›Full record

ArticleInternational health2019

Pilot testing of an online training module about screening for acute HIV infection in adult patients seeking urgent healthcare.

Hannah Rafferty, Oscar Chirro, Clifford Oduor, Elizabeth Wahome, Caroline Ngoi, Elise van der Elst, René Berger, Sarah Rowland-Jones, Susan M Graham, Eduard J Sanders

Open access · hybridAbstract read
In one paragraph

Article in International health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Clinical Application Evaluation of ElecsysFrontiers in cellular and infection microbiology · 2022
    Article
  3. Review
  4. Article
  5. Symptom-based Scoring for Acute Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Hannah RaffertyKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Oscar ChirroKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Clifford OduorKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Elizabeth WahomeKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Caroline NgoiKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Elise van der ElstKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
René BergerUnited States Agency for International Development (USAID), Nairobi, Kenya.
Sarah Rowland-JonesNuffield Department of Medicine, University of Oxford, Headington, Oxford, UK.
Susan M GrahamUniversity of Washington, 359909, 325 Ninth Avenue, Seattle, WA, USA.
Eduard J SandersKEMRI/Wellcome Trust Research Programme Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Kenya Medical Research Institute · KEUnited States Agency for International Development · USUniversity of Oxford · GBUniversity of Washington · US

Funding

Impact of a novel screening program to detect acute and prevalent HIV infection and reduce HIV transmissionR01AI124968 · NIAID · UNIVERSITY OF WASHINGTON · PI GRAHAM, SUSAN MARIE, SANDERS, EDUARD · 2016 to 2019
$2.3M
NIAID NIH HHS R01 AI124968Wellcome TrustWellcome Trust 203077/Z/16/Z
6 · The paper itself

Abstract

backgroundAcute HIV infection (AHI) is the phase of HIV infection immediately after acquisition, during which many patients develop symptoms and often seek healthcare. However, clinicians in sub-Saharan Africa are not currently taught about AHI.

methodsThis study pilot-tested a self-directed AHI training module among clinical officers (COs) in coastal Kenya and assessed knowledge gained and challenges to instituting screening. The training module included four domains: AHI definition and importance of AHI recognition; symptoms and screening algorithms; diagnostic strategies; and management. AHI knowledge was assessed before and immediately after training. Participants' ability to utilize an AHI screening algorithm was evaluated with a case-based exercise.

resultsSelf-directed training was completed by 45 COs. Pre-test scores were low (median score 35% IQR 30-45%), but improved significantly after training (median post-test score 75%, IQR 70-85%, Wilcoxon signed-rank test p<0.0001). Participants had challenges in understanding the utility and application of a screening algorithm to identify patients for whom AHI testing would be indicated. Knowledge of AHI was poor at baseline, but improved with self-directed learning. Based on these findings, we revised and improved the AHI training module and pre- and post-assessments, which are now freely available online at www.marps-africa.org.

conclusionsGuidelines on AHI screening and diagnosis are urgently needed in high HIV transmission areas.

Indexed as

Education, DistanceMass ScreeningAcute DiseaseAdolescentAdultAlgorithmsAmbulatory CareClinical CompetenceFemaleHIV InfectionsHumansKenyaMalePatient Acceptance of Health CarePhysicians, Primary CarePilot Projectsacute HIV infectionfebrile patientonline learningscreening algorithmself-directed learning

Identifiers

PMID30388277
PMCPMC6398591
OpenAlexW2898889103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.