Evidence map›Paper›PMID 30388232›Full record

ArticleThe Journal of infectious diseases2019

Genital Wart Recurrence Among Men Residing in Brazil, Mexico, and the United States.

Anna R Giuliano, Bradley Sirak, Martha Abrahamsen, Roberto J C Silva, Maria L Baggio, Lenice Galan, Ricardo C Cintra, Eduardo Lazcano-Ponce, Luisa L Villa

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Anna R GiulianoCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, Florida.
Bradley SirakCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, Florida.
Martha AbrahamsenCenter for Infection Research in Cancer, Moffitt Cancer Center, Tampa, Florida.
Roberto J C SilvaCentro de Referência e Treinamento em DST/AIDS, Programa Estadual de DST/AIDS.
Maria L BaggioCentro de Investigação Translacional em Oncologia, Instituto do Cancer do Estado de São Paulo, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo.
Lenice GalanLudwig Institute for Cancer Research.
Ricardo C CintraInstituto de Química, Departamento de Bioquímica, Universidade de São Paulo, Brazil.
Eduardo Lazcano-PonceCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, México.
Luisa L VillaInstituto de Química, Departamento de Bioquímica, Universidade de São Paulo, Brazil.
Moffitt Cancer Center · USUniversidade de São Paulo · BRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstituto Nacional de Salud Pública · MX

Funding

Natural History of HPV Infection in Men: The HIM StudyR01CA098803 · NCI · H. LEE MOFFITT CANCER CTR &RES INST · PI GIULIANO, ANNA R. · 2004 to 2014
$18.2M
NCI NIH HHS R01 CA098803
6 · The paper itself

Abstract

backgroundGenital wart (GW) incidence is high among men. The percentage and rate at which subsequent GW events occur are understudied. The purpose of this study was to describe the rate of subsequent GWs, associated human papillomavirus (HPV) types, and time to subsequent GW event among unvaccinated men.

methodsThe study was nested within a multinational prospective HPV natural history study of men aged 18-70 years in the United States, Mexico, and Brazil, examined every 6 months for a median follow-up of 50.4 months. Subsequent GW events were defined as GWs detected after ≥16 weeks of the prior event.

resultsForty-four percent of men experienced ≥1 GW following the initial episode. Men with ≥2 subsequent events were at highest risk of continued GW experiences, with as high as 10 postinitial GW events. The incidence rate of each subsequent GW increased with increasing events (incidence of first subsequent event was 13.1 vs 36.6/1000 person-months for the fourth event). The proportion of GWs among HPV-6 and/or -11-positive patients remained constant across events. Approximately 63%-69% were positive for ≥1 of the 9-valent HPV vaccine types.

conclusionsThese data highlight the high burden of GWs among men across the lifespan and the need for vaccination to prevent multiple GW episodes.

Indexed as

AdolescentAdultAgedBrazilCondylomata AcuminataFollow-Up StudiesHumansIncidenceMaleMexicoMiddle AgedPapillomaviridaeProspective StudiesRecurrenceUnited StatesYoung Adultgenital wartsHPVvaccination

Identifiers

PMID30388232
PMCPMC6376908
OpenAlexW2898895815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.