Evidence map›Paper›PMID 30387896›Full record

ArticleThe American journal on addictions2018

Neuropsychological changes in patients with substance use disorder after completion of a one month intensive outpatient treatment program.

James W McKowen, Benjamin M Isenberg, Nicholas W Carrellas, Courtney A Zulauf, Nalan E Ward, Ronna S Fried, Timothy E Wilens

Open access · greenAbstract read
In one paragraph

Article in The American journal on addictions, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

James W McKowenAddiction Recovery Management Service and West End Clinic, Massachusetts General Hospital, Boston, Massachusetts.
Benjamin M IsenbergClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts.
Nicholas W CarrellasClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts.
Courtney A ZulaufClinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Boston, Massachusetts.
Nalan E WardAddiction Recovery Management Service and West End Clinic, Massachusetts General Hospital, Boston, Massachusetts.
Ronna S FriedDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Timothy E WilensDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Massachusetts General Hospital · USHarvard University · US

Funding

The National Drug Abuse Treatment Clinical Trials NetworkUG1DA015831 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Roger D. Weiss · 2015 to 2026
$110.8M
NIDA NIH HHS 3UG1DA015831NIDA NIH HHS UG1 DA015831
6 · The paper itself

Abstract

BACKGROUND AND

objectivesData suggest individuals with substance use disorders (SUD) exhibit high rates of executive functioning (EF) impairment, and that EF level can predict treatment retention. The primary aim of the present study was to investigate if patients who completed a 1 month intensive outpatient program (IOP) for SUD demonstrated recovered EF.

methodsBaseline and follow-up neurocognitive functioning was assessed by the Cambridge Neuropsychological Test Automated Battery (CANTAB) and the self-reported Behavior Rating Inventory of Executive Functioning (BRIEF-A) questionnaire.

resultsThe final sample included 15 patients who completed the one month IOP and for whom data were available (53% male, aged 36 years ± 13.4). Despite exhibiting general improvements in EF and significant improvements in organization, subjects continued to manifest significant executive dysfunction as evaluated by self-report and computerized assessment. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Patients with SUD often manifest high levels of executive dysfunction upon entry into SUD treatment that, while improving minimally, appears to persist despite intensive outpatient treatment at 1 month. These persistent EF deficits may affect patient engagement and participation in treatment, thus necessitating SUD programs to assess and accommodate EF issues throughout treatment. (Am J Addict 2018;XX:1-7).

Indexed as

Executive FunctionSubstance-Related DisordersAdultAmbulatory CareBehavioral SymptomsFemaleHumansMaleMental Status and Dementia TestsMiddle AgedNeuropsychological TestsOutpatientsSelf ReportSurveys and QuestionnairesTreatment OutcomeYoung Adult

Identifiers

PMID30387896
PMCPMC11006117
OpenAlexW2899026412

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.