Evidence map›Paper›PMID 30387695›Full record

ReviewPersonalized medicine2018

Data integration strategies for predictive analytics in precision medicine.

Lewis J Frey

Abstract readReview
In one paragraph

Review in Personalized medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Medical Big Data Storage in Precision Medicine: A Systematic Review.Journal of biomedical physics & engineering · 2025
    Article
  2. Article
  3. Article
  4. Informatics Ecosystems to Advance the Biology of Glycans.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Lewis J FreyBiomedical Informatics Center, Medical University of South Carolina, 135 Cannon Street/Suite 405K, MSC 200, Charleston, SC 29425, USA.

Funding

Subproject Title: Clinical Research Education, Mentoring and Career Development CoreU54GM104941 · NIGMS · UNIVERSITY OF DELAWARE · PI Megan M Wenner · 2013 to 2026
$60.5M
Sociobiological Responses to Stress in Prostate Cancer SurvivorsU54MD010706 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ETHIER, STEPHEN P., HUGHES-HALBERT, CHANITA A. · 2016 to 2020
$8.0M
Techniques to Integrate Disparate Data: Clinical Personalized Pragmatic PredictioR01GM108346 · NIGMS · UNIVERSITY OF UTAH · PI FREY, LEWIS JAMES, LENERT, LESLIE A. · 2013 to 2016
$2.1M
NIGMS NIH HHS R01 GM108346NIGMS NIH HHS U54 GM104941NIMHD NIH HHS U54 MD010706
6 · The paper itself

Abstract

With the rapid growth of health-related data including genomic, proteomic, imaging and clinical, the arduous task of data integration can be overwhelmed by the complexity of the environment including data size and diversity. This report examines the role of data integration strategies for big data predictive analytics in precision medicine research. Infrastructure-as-code methodologies will be discussed as a means of integrating and managing data. This includes a discussion on how and when these strategies can be used to lower barriers and address issues of consistency and interoperability within medical research environments. The goal is to support translational research and enable healthcare organizations to integrate and utilize infrastructure to accelerate the adoption of precision medicine.

Indexed as

Biomedical ResearchDatabases, FactualData Interpretation, StatisticalElectronic Health RecordsForecastingGenomicsHumansPrecision MedicineProteomicsTranslational Research, Biomedicalcommon data modelsdata integrationinfrastructureinfrastructure-as-codeinteroperabilitymultiomicsprecision medicinepredictive analyticssociotechnicalvirtual machines

Identifiers

PMID30387695
PMCPMC6277956

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.