Evidence map›Paper›PMID 30387334›Full record

ArticleJournal of Zhejiang University. Science. B

Effect of a combination of astaxanthin supplementation, heat stress, and intermittent reloading on satellite cells during disuse muscle atrophy.

Toshinori Yoshihara, Takao Sugiura, Nobuyuki Miyaji, Yuki Yamamoto, Tsubasa Shibaguchi, Ryo Kakigi, Hisashi Naito, Katsumasa Goto, Daijiro Ohmori, Toshitada Yoshioka

Open access · bronzeAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Effects of astaxanthin on the protection of muscle health (Review).Experimental and therapeutic medicine · 2020
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Toshinori YoshiharaGraduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan.
Takao SugiuraFaculty of Education, Yamaguchi University, Yamaguchi, Yamaguchi 753-8513, Japan.
Nobuyuki MiyajiToyo Koso Kagaku Co. Ltd., Urayasu, Chiba 279-0041, Japan.
Yuki YamamotoInstitute of Health and Sports Science, Kurume University, Kurume, Fukuoka 839-8502, Japan.
Tsubasa ShibaguchiInstitute of Liberal Arts and Science, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
Ryo KakigiFaculty of Medicine, Juntendo University, Bunkyo-ku, Tokyo 113-0033, Japan.
Hisashi NaitoGraduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 270-1695, Japan.
Katsumasa GotoGraduate School of Health Sciences, Toyohashi SOZO University, Toyohashi, Aichi 440-8511, Japan.
Daijiro OhmoriDepartment of Chemistry, School of Medicine, Juntendo University, Inzai, Chiba 270-1695, Japan.
Toshitada YoshiokaHirosaki Gakuin University, Hirosaki, Aomori 036-8577, Japan.
Juntendo University · JPHirosaki Gakuin University · JPKanazawa University · JPKurume University · JPToyo Engineering (Japan) · JPToyohashi Sozo College · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We examined the effect of a combination of astaxanthin (AX) supplementation, repeated heat stress, and intermittent reloading (IR) on satellite cells in unloaded rat soleus muscles. Forty-nine male Wistar rats (8-week-old) were divided into control, hind-limb unweighting (HU), IR during HU, IR with AX supplementation, IR with repeated heat stress (41.0-41.5 °C for 30 min), and IR with AX supplementation and repeated heat stress groups. After the experimental period, the antigravitational soleus muscle was analyzed using an immunohistochemical technique. Our results revealed that the combination of dietary AX supplementation and heat stress resulted in protection against disuse muscle atrophy in the soleus muscle. This protective effect may be partially due to a higher satellite cell number in the atrophied soleus muscle in the IR/AX/heat stress group compared with the numbers found in the other groups. We concluded that the combination treatment with dietary AX supplementation and repeated heat stress attenuates soleus muscle atrophy, in part by increasing the number of satellite cells.

Indexed as

Dietary SupplementsHeat-Shock ResponseAnimalsBody WeightFibrinolytic AgentsHindlimbHot TemperatureImmunohistochemistryMaleMuscle, SkeletalMuscular AtrophyOxidative StressRatsRats, WistarSatellite Cells, Skeletal MuscleXanthophyllsastaxanthineFibrinolytic AgentsXanthophyllsAntioxidant astaxanthin; Disuse muscle atrophy; Heat stress; Satellite cell

Identifiers

PMID30387334
PMCPMC6238114
OpenAlexW2902312949

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.