Evidence map›Paper›PMID 30387294›Full record

ArticleJournal of applied clinical medical physics2019

External dosimetry audit for quality assurance of carbon-ion radiation therapy clinical trials.

Hideyuki Mizuno, Akifumi Fukumura, Nobuyuki Kanematsu, Shunsuke Yonai, Toshiyuki Shirai, Ken Yusa, Toshihiro Yanou, Masaki Suga, Manabu Mizota, Shinichi Minohara and 2 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hideyuki MizunoNational Institute of Radiological Sciences, QST, Chiba, Japan.
Akifumi FukumuraNational Institute of Radiological Sciences, QST, Chiba, Japan.
Nobuyuki KanematsuNational Institute of Radiological Sciences, QST, Chiba, Japan.
Shunsuke YonaiNational Institute of Radiological Sciences, QST, Chiba, Japan.
Toshiyuki ShiraiNational Institute of Radiological Sciences, QST, Chiba, Japan.
Ken YusaGunma University Heavy Ion Medical Center, Gunma, Japan.
Toshihiro YanouHyogo Ion Beam Medical Center, Tatsuno, Hyōgo, Japan.
Masaki SugaHyogo Ion Beam Medical Center, Tatsuno, Hyōgo, Japan.
Manabu MizotaIon Beam Therapy Center, SAGA HIMAT Foundation, Saga, Japan.
Shinichi MinoharaKanagawa Cancer Center, Kanagawa, Japan.
Tatsuaki KanaiGunma University Heavy Ion Medical Center, Gunma, Japan.
Tadashi KamadaNational Institute of Radiological Sciences, QST, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe QA team of the Japan carbon-ion radiation oncology study group (J-CROS) was organized in 2015 to enhance confidence in the accuracy of clinical dosimetry and ensure that the facility QA procedures are adequate. The team conducted onsite dosimetry audits in all the carbon-ion radiation therapy centers in Japan. MATERIALS AND

methodsA special phantom was fabricated for the onsite dosimetry audit. Target volumes such as the GTV, CTV, and PTV were contoured to the obtained CT images, and two plans with different isocenter depths were created. The dose at the isocenter was measured by an ionization chamber, in the onsite audit and compared with the calculated dose.

resultsFor all the centers, the average of the percentage ratio between the measured and calculated doses (measured/calculated) was 0.5% (-2.7% to +2.6%) and the standard deviation, 1.7%. In all the centers, the beams were within the set tolerance level of 3%.

conclusionsThe audit demonstrated that the dose at a single point in the water phantom was within tolerance, but it is a big step to say that all doses are correct. In addition, this external dosimetry audit encouraged centers to improve the quality of their dosimetry systems.

Indexed as

Clinical Trials as TopicHeavy Ion RadiotherapyPhantoms, ImagingAlgorithmsHumansNeoplasmsQuality Assurance, Health CareRadiation DosageRadiometryRadiotherapy Planning, Computer-Assistedcarbon-ion radiation therapyclinical trialmulticenter dosimetryonsite dosimetry auditquality assurance

Identifiers

PMID30387294
PMCPMC6333139

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.