ArticleMolecular imaging and biology2019
Characterization of Brown Adipose Tissue in a Diabetic Mouse Model with Spiral Volumetric Optoacoustic Tomography.
Article in Molecular imaging and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Ultrawideband high density polymer-based spherical array for real-time functional optoacoustic micro-angiography.Light, science & applications · 2025Article
- Photoacoustic imaging: a unique imaging examination for the assessment of diabetic vascular disease.Frontiers in clinical diabetes and healthcare · 2025Review
- Spiral volumetric optoacoustic and ultrasound (SVOPUS) tomography of mice.Photoacoustics · 2024Article
- Spiral scanning and self-supervised image reconstruction enable ultra-sparse sampling multispectral photoacoustic tomography.Photoacoustics · 2024Article
- Rat perivascular adipose tissue microvasculature revealed by tissue clearing.Frontiers in physiology · 2024Article
- Emerging technologies in adipose tissue research.Adipocyte · 2023Review
- Review of Three-Dimensional Handheld Photoacoustic and Ultrasound Imaging Systems and Their Applications.Sensors (Basel, Switzerland) · 2023Review
- Recent development of near-infrared photoacoustic probes based on small-molecule organic dye.RSC chemical biology · 2021Review
- Photoacoustic Imaging Probes Based on Tetrapyrroles and Related Compounds.International journal of molecular sciences · 2020Review
- Multifocal structured illumination optoacoustic microscopy.Light, science & applications · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDiabetes is associated with a deterioration of the microvasculature in brown adipose tissue (BAT) and with a decrease in its metabolic activity. Multispectral optoacoustic tomography has been recently proposed as a new tool capable of differentiating healthy and diabetic BAT by observing hemoglobin gradients and microvasculature density in cross-sectional (2D) views. We report on the use of spiral volumetric optoacoustic tomography (SVOT) for an improved characterization of BAT. PROCEDURES: A streptozotocin-induced diabetes model and control mice were scanned with SVOT. Volumetric oxygen saturation (sO
resultsScanning revealed a 46 % decrease in TBV and a 25 % decrease in sO
conclusionsThese results suggest that SVOT may serve as an effective tool for studying the effects of diabetes on BAT. The volumetric optoacoustic imaging probe used for the SVOT scans can be operated in a handheld mode, thus potentially providing a clinical translation route for BAT-related studies with this imaging technology.
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