Evidence map›Paper›PMID 30387017›Full record

ReviewMagma (New York, N.Y.)2019

A

Jean-Pierre Raufman, Melissa Metry, Jessica Felton, Kunrong Cheng, Su Xu, James Polli

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Magma (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Novel nitroxide-bile acid conjugates inform substrate requirements for human bile acid transporters.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2023
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jean-Pierre RaufmanDivision of Gastroenterology and Hepatology, Department of Medicine, and Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, and the VA Maryland Healthcare System, Baltimore, MD, 21201, USA. jraufman@som.umaryland.edu.ORCID http://orcid.org/0000-0002-6340-4382
Melissa MetryDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, 21201, USA.
Jessica FeltonDepartment of Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
Kunrong ChengDivision of Gastroenterology and Hepatology, Department of Medicine, and Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, and the VA Maryland Healthcare System, Baltimore, MD, 21201, USA.
Su XuDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.
James PolliDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, 21201, USA.
University of Maryland, Baltimore · US

Funding

Research Training in Gastroenterology and HepatologyT32DK067872 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RAUFMAN, JEAN-PIERRE · 2005 to 2024
$7.2M
Creating a toolkit to measure in vivo bile acid transportR21DK093406 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI POLLI, JAMES E, RAUFMAN, JEAN-PIERRE · 2012 to 2013
$404k
M3R, MMP1 and Colon Cancer DisseminationI01BX002129 · VA · BALTIMORE VA MEDICAL CENTER · PI RAUFMAN, JEAN-PIERRE · 2015 to 2018
–
BLRD VA I01 BX002129NIDDK NIH HHS DK067872NIDDK NIH HHS DK093406NIDDK NIH HHS R21 DK093406NIDDK NIH HHS T32 DK067872U.S. Department of Veterans Affairs BX002129
6 · The paper itself

Abstract

In up to 50% of people diagnosed with a common ailment, diarrhea-predominant irritable bowel syndrome, diarrhea results from excess spillage of bile acids into the colon-data emerging over the past decade identified deficient release of a gut hormone, fibroblast growth factor 19 (FGF19), and a consequent lack of feedback suppression of bile acid synthesis as the most common cause.

Indexed as

Fluorine-19 Magnetic Resonance ImagingAnimalsBile Acids and SaltsBiological TransportDiagnostic Tests, RoutineDiarrheaFemaleFibroblast Growth FactorsGallbladderHumansIntestinesMaleMaterials TestingMiceMice, KnockoutOrganic Anion Transporters, Sodium-DependentBile Acids and Saltsfibroblast growth factor 15, mouseFibroblast Growth FactorsOrganic Anion Transporters, Sodium-DependentSelenium-75Selenium Radioisotopessodium-bile acid cotransporterSymportersTaurocholic Acid19F MRIBile acidsDiarrheaEnterohepatic circulationGallbladderIrritable bowel syndrome

Identifiers

PMID30387017
PMCPMC6408933
OpenAlexW2899008879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.