Evidence map›Paper›PMID 30386998›Full record

ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2019

The incidence of symptomatic in-hospital VTEs in Asian patients undergoing joint arthroplasty was low: a prospective, multicenter, 17,660-patient-enrolled cohort study.

Yi Zeng, Haibo Si, Yuangang Wu, Jing Yang, Zongke Zhou, Pengde Kang, Fuxing Pei, Bin Shen

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of Atorvastatin Against Venous Thromboembolism After Total Hip Arthroplasty.Journal of musculoskeletal & neuronal interactions · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yi ZengDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Haibo SiDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Yuangang WuDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Jing YangDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Zongke ZhouDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Pengde KangDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Fuxing PeiDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Bin ShenDepartment of Orthopaedic Surgery, West China Medical School, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China. shenbin_1971@163.com.
Sichuan University · CN

Funding

Department of Science and Technology of Sichuan Province 2018HH0141Health Department of Sichuan Province 18ZD016National Natural Science Foundation of China 81601936
6 · The paper itself

Abstract

purposeThe aim of this study was to determine the real incidence of symptomatic in-hospital venous thromboembolism (VTE) and identify risk factors for VTEs in Asian patients undergoing total hip (THA) and total knee arthroplasty (TKA).

methodsA total of 17,660 patients (20,078 hips and knees) undergoing THA and TKA at 78 hospitals were enrolled. The composite incidence of symptomatic in-hospital DVT and PE was identified as the primary effectiveness outcomes. The primary safety outcomes were the incidences of postoperative complications, especially for major or minor bleeding. Secondary analyses were assessed to identify the risk factors for postoperative VTE.

resultsThe overall rates of symptomatic in-hospital DVT in patients undergoing THA and TKA were 0.21% (19/9022) and 0.36% (31/8638), respectively. Symptomatic PE was confirmed in one TKA patient. Safety analysis showed that the incidence of bleeding during hospital stays in patients undergoing THA and TKA was 0.10% (18/17,660). Increased VTE risks were associated with old age, high BMI index, hypertension, cerebrovascular disease, history of venous thromboembolism and no medical prophylaxis usage.

conclusionsThe incidence of symptomatic VTEs in Asian regions was low compared with that reported in studies targeting Western populations. Approximately 1 in 500 patients undergoing THA and approximately 1 in 300 patients undergoing TKA developed symptomatic VTEs prior to hospital discharge. Old age, high BMI, history of venous thromboembolism, hypertension, cerebrovascular disease, and no medication prophylaxis were risk factors identified in this study. LEVEL OF EVIDENCE: Prospective cohort study; Level 2.

Indexed as

AgedAnticoagulantsArthroplasty, Replacement, HipChinaFemaleHumansIncidenceMaleMiddle AgedPostoperative ComplicationsPrognosisProspective StudiesRisk FactorsVenous ThromboembolismAnticoagulantsDeep vein thrombosisIncidencePulmonary embolismRisk factorsTKATKRTotal hip arthroplastyTotal knee arthroplastyTotal knee replacementVenous thromboembolism

Identifiers

PMID30386998
OpenAlexW2899498834

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.