Evidence map›Paper›PMID 30386949›Full record

ArticleJapanese journal of ophthalmology2019

Management of presumed trematode induced granulomatous uveitis in pediatric patients.

Rowayda Mohamed Amin, Alaa E Radwan, Mohamed B Goweida, Hesham F El Goweini, Ahmed M Bedda, Wael M Lotfy, Ahmed R H Ahmed

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Japanese journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06260449 (Different Treatment Approaches of Presumed Trematode-Induced Uveitis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06260449 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Different Treatment Approaches of Presumed Trematode-Induced Uveitis

TypeinterventionalSponsorAssiut UniversityRan2023 to 2024Enrolled31ConditionsUveitisArmsSurgical removal
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Rowayda Mohamed AminOphthalmology Department, Faculty of Medicine, Alexandria University, Khartoum Square, Alexandria, Egypt. r_mohamed2002040@alexmed.edu.eg.
Alaa E RadwanInternational Eye Clinic, Sohâg, Egypt.
Mohamed B GoweidaOphthalmology Department, Faculty of Medicine, Alexandria University, Khartoum Square, Alexandria, Egypt.
Hesham F El GoweiniOphthalmology Department, Faculty of Medicine, Alexandria University, Khartoum Square, Alexandria, Egypt.
Ahmed M BeddaOphthalmology Department, Faculty of Medicine, Alexandria University, Khartoum Square, Alexandria, Egypt.
Wael M LotfyParasitology Department, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Ahmed R H AhmedPathology Department, Faculty of Medicine, Sohag University, Sohâg, Egypt.
Alexandria University · EGEgypt Nanotechnology Center · EGNational Research Centre · EGSohag University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo outline the management of newly identified trematode induced uveitis in pediatric patients STUDY

designProspective interventional case series

methodsPatients with distinctive uveitis were recruited to either receive steroid monotherapy or undergo surgical excision of the inflammatory lesions based on a scoring system. Outcome measures included best corrected visual acuity (BCVA), intraocular inflammatory activity, and incidence of ophthalmic complications

results170 patients (174 eyes) were recruited. Mean age was 11.1 years. Mean initial decimal BCVA (± SD) was 0.58 (± 0.31). Of 116 eyes with disease scores <5, 109 were treated effectively with steroids (93.97%). Surgical excision was offered to 58 patients and proved curative in the treated eyes. Protracted inflammation with persistence of the granulomas was noted in 5 patients refusing surgery. Mean follow up period was 21.5 months. Mean final BCVA was 0.69 (±0.27). A significant change in BCVA was noted (p=0.002). There has not been a need for retreatment in any of the study patients, who were also given instructions on evading exposure to fresh water habitats. Larger lesions, mixed disease morphology, older age at presentation were associated with higher rates of ophthalmic complications and vision loss

conclusionA novel waterborne trematode inducing uveitis has been identified in Egypt. A favorable response to steroid monotherapy is demonstrated in low grade disease, while surgical excision was found to be curative in patients with larger lesions or those showing suboptimal response to medical treatment.

Indexed as

AdolescentAnimalsAnthelminticsChildChild, PreschoolDisease ManagementEye Infections, ParasiticFemaleGranulomaHumansMaleOphthalmologic Surgical ProceduresProspective StudiesTrematodaTrematode InfectionsUveitisAnthelminticsEgyptGranulomatous uveitisInfectionsRiver NileTreatment

Identifiers

PMID30386949
OpenAlexW2898995100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.