Evidence map›Paper›PMID 30386878›Full record

ArticleEuropean biophysics journal : EBJ2019

Cell-based assays and molecular dynamics analysis of a boron-containing agonist with different profiles of binding to human and guinea pig beta2 adrenoceptors.

Marvin A Soriano-Ursúa, Martiniano Bello, Christian F Hernández-Martínez, Iván Santillán-Torres, Ruth Guerrero-Ramírez, José Correa-Basurto, José-Antonio Arias-Montaño, José G Trujillo-Ferrara

Abstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. In silico identification of a biarylamine acting as agonist at human βNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Article
  2. Review
  3. Article
  4. Interactions of a boron-containing levodopa derivative on DJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2022
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marvin A Soriano-UrsúaDepartamentos de Fisiología, Bioquímica y Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340, Ciudad de México, Mexico. msoriano@ipn.mx.ORCID http://orcid.org/0000-0002-6529-1502
Martiniano BelloDepartamentos de Fisiología, Bioquímica y Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340, Ciudad de México, Mexico.
Christian F Hernández-MartínezDepartamentos de Fisiología, Bioquímica y Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340, Ciudad de México, Mexico.
Iván Santillán-TorresDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del I.P.N., Av. Instituto Politécnico Nacional 2508, 07360, Ciudad de México, Mexico.
Ruth Guerrero-RamírezDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del I.P.N., Av. Instituto Politécnico Nacional 2508, 07360, Ciudad de México, Mexico.
José Correa-BasurtoDepartamentos de Fisiología, Bioquímica y Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340, Ciudad de México, Mexico.ORCID http://orcid.org/0000-0002-4973-5265
José-Antonio Arias-MontañoDepartamento de Fisiología, Biofísica y Neurociencias, Centro de Investigación y de Estudios Avanzados del I.P.N., Av. Instituto Politécnico Nacional 2508, 07360, Ciudad de México, Mexico.
José G Trujillo-FerraraDepartamentos de Fisiología, Bioquímica y Laboratorio de Modelado Molecular, Bioinformática y Diseño de Fármacos, Sección de Estudios de Posgrado e Investigación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón s/n, 11340, Ciudad de México, Mexico. jtrujillo@ipn.mx.ORCID http://orcid.org/0000-0002-1979-6489
Instituto Politécnico Nacional · MX

Funding

Comisión de Operación y Fomento de Actividades Académicas, Instituto Politécnico Nacional M1930Consejo Nacional de Ciencia y Tecnología CB235785
6 · The paper itself

Abstract

The design of beta2 adrenoceptor (β

Indexed as

Molecular Dynamics SimulationAdrenergic beta-2 Receptor AgonistsAnimalsBoron CompoundsCHO CellsCricetulusGuinea PigsHumansMolecular Docking SimulationProtein BindingProtein ConformationReceptors, Adrenergic, beta-2ThermodynamicsAdrenergic beta-2 Receptor AgonistsBoron CompoundsReceptors, Adrenergic, beta-2AdrenoceptorBoronCell-based assaysComparative physiologyGPCRPharmacology

Identifiers

PMID30386878
OpenAlexW2899513569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.