Evidence map›Paper›PMID 30386807›Full record

ArticleOpen forum infectious diseases2018

Care of Ebola Survivors and Factors Associated With Clinical Sequelae-Monrovia, Liberia.

A de St Maurice, E Ervin, R Orone, M Choi, E K Dokubo, P E Rollin, S T Nichol, D Williams, J Brown, R Sacra and 2 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Use of Ebola Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2020.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021
    Guideline
  4. Pooled it
  5. Pooled it
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Post-Ebola Symptoms 7 Years After Infection: The Natural History of Long Ebola.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  13. Review
  14. Review
  15. Article
  16. Post-Ebola Syndrome Presents With Multiple Overlapping Symptom Clusters: Evidence From an Ongoing Cohort Study in Eastern Sierra Leone.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  17. Review
  18. Long-term Complications of Ebola Virus Disease: Prevalence and Predictors of Major Symptoms and the Role of Inflammation.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

A de St MauriceViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0001-7368-7403
E ErvinViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
R OroneELWA Hospital, Monrovia, Liberia.
M ChoiViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
E K DokuboCenters for Disease Control and Prevention, Monrovia, Liberia.
P E RollinViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
S T NicholViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
D WilliamsCenters for Disease Control and Prevention, Monrovia, Liberia.
J BrownELWA Hospital, Monrovia, Liberia.
R SacraELWA Hospital, Monrovia, Liberia.
J FankhauserELWA Hospital, Monrovia, Liberia.
B KnustViral Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia.
Centers for Disease Control and Prevention · USUniversity of Liberia · LR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Eternal Love Winning Africa (ELWA) Clinic was the first clinic to provide free, comprehensive care to Ebola virus disease (EVD) survivors in Liberia. The objectives of this analysis were to describe the demographics and symptoms of EVD survivors at ELWA from January 2015 through March 2017 and to identify risk factors for development of sequelae.

methodsPatients' demographic and clinical information was collected by chart review in June 2016 and March 2017. Associations with clinical sequelae were analyzed using the chi-square test,

resultsFrom January 2015 to March 2017, 329 EVD survivors were evaluated at ELWA. Most survivors experienced myalgia/arthralgia (73%; n = 239) and headache (53%; n = 173). The length of time from Ebola Treatment Unit (ETU) discharge to first clinic visit ranged from 0 to 30 months. Many visits (30%) occurred 24 or more months after ETU discharge. The proportion of visits for headache, weight loss, joint pain, visual problems, insomnia, fatigue, memory loss, decreased libido, depression, and uveitis decreased over time. More men than women had visits for depression; however, these differences were not significant. Symptom prevalence differed in adults and children; significantly more adults experienced myalgia/arthralgia (77% vs 44%), visual problems (41% vs 12%), post-EVD-related musculoskeletal pain (42% vs 15%), and insomnia (17% vs 2%).

conclusionsEVD survivors frequented ELWA for EVD-related symptoms many months after ETU discharge, indicating a long-term need for care. Reported symptoms changed over time, which may reflect eventual resolution of some sequelae.

Indexed as

EbolaELWA hospitalLiberiaMonroviasurvivors

Identifiers

PMID30386807
PMCPMC6202424
OpenAlexW2893143013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.