Evidence map›Paper›PMID 30386778›Full record

ArticleFrontiers in bioengineering and biotechnology2018

New Thermophilic α/β Class Epoxide Hydrolases Found in Metagenomes From Hot Environments.

Erica Elisa Ferrandi, Christopher Sayer, Simone Antonio De Rose, Elisa Guazzelli, Carlotta Marchesi, Vahid Saneei, Michail N Isupov, Jennifer A Littlechild, Daniela Monti

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. The Impact of Metagenomics on Biocatalysis.Angewandte Chemie (International ed. in English) · 2024
    Review
  3. Extremophiles in a changing world.Extremophiles : life under extreme conditions · 2024
    Review
  4. Epoxide Hydrolases: Multipotential Biocatalysts.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erica Elisa FerrandiIstituto di Chimica del Riconoscimento Molecolare, C.N.R., Milan, Italy.
Christopher SayerThe Henry Wellcome Building for Biocatalysis, Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Simone Antonio De RoseThe Henry Wellcome Building for Biocatalysis, Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Elisa GuazzelliIstituto di Chimica del Riconoscimento Molecolare, C.N.R., Milan, Italy.
Carlotta MarchesiIstituto di Chimica del Riconoscimento Molecolare, C.N.R., Milan, Italy.
Vahid SaneeiThe Henry Wellcome Building for Biocatalysis, Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Michail N IsupovThe Henry Wellcome Building for Biocatalysis, Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Jennifer A LittlechildThe Henry Wellcome Building for Biocatalysis, Biosciences, College of Life and Environmental Sciences, University of Exeter, Exeter, United Kingdom.
Daniela MontiIstituto di Chimica del Riconoscimento Molecolare, C.N.R., Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two novel epoxide hydrolases (EHs), Sibe-EH and CH65-EH, were identified in the metagenomes of samples collected in hot springs in Russia and China, respectively. The two α/β hydrolase superfamily fold enzymes were cloned, over-expressed in

Indexed as

epoxide hydrolaseindustrial biocatalysismetagenomicsprotein structurestereoselectivity

Identifiers

PMID30386778
PMCPMC6198070

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.