Evidence map›Paper›PMID 30386717›Full record

ArticleCurrent epidemiology reports2018

Missingness in the Setting of Competing Risks: from missing values to missing potential outcomes.

Bryan Lau, Catherine Lesko

Abstract read
In one paragraph

Article in Current epidemiology reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
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  9. Article
  10. Causal inference in the face of competing events.Current epidemiology reports · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Bryan LauDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Catherine LeskoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

Funding

ECHODAC (Environmental Influences on Child Health Outcomes Data Analysis Center)U24OD023382 · OD · JOHNS HOPKINS UNIVERSITY · PI Diane J Catellier, LISA P JACOBSON · 2016 to 2026
$148.4M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
Lung and HIV Analytical Data Coordinating Center (LHAD-CC)U01HL121812 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI LAU, BRYAN · 2013 to 2017
$3.4M
NHLBI NIH HHS U01 HL121812NIAAA NIH HHS U01 AA020793NIAID NIH HHS P30 AI094189NIH HHS U24 OD023382
6 · The paper itself

Abstract

purpose of reviewThe setting of competing risks in which there is an event that precludes the event of interest from occurring is prevalent in epidemiological research. Unless studying all-cause mortality, any study following up individuals is subject to having a competing risk should individuals die during time period that the study covers. While there are prior papers discussing the need for competing risk methods in epidemiologic research, we are not aware of any review that discusses issues of missing data in a competing risk setting. RECENT

findingsWe provide an overview of causal inference in competing risks as potential outcomes are missing, provide some strategies in dealing with missing (or misclassified) event type, and missing covariate data in competing risks. The strategies presented are specifically focused on those that may easily be implemented in standard statistical packages. There is ongoing work in terms of causal analyses, dealing with missing event type information, and missing covariate values specific to competing risk analyses. SUMMARY: Competing events are common in epidemiologic research. While there has been a focus on why one should conduct a proper competing risk analysis, a perhaps unrecognized issue is in terms of missingness. Strategies exist to minimize the impact of missingness in analyses of competing risks.

Indexed as

causalitycause-specific hazardCompeting risksimputationmissing datasubdistribution hazard

Identifiers

PMID30386717
PMCPMC6205187

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.