Evidence map›Paper›PMID 30386610›Full record

ArticleUnited European gastroenterology journal2018

The XL probe: A luxury or a necessity? Risk stratification in an obese community cohort using transient elastography.

Rebecca Harris, Timothy R Card, Toby Delahooke, Guruprasad P Aithal, I Neil Guha

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. [Research progress of non-invasive examination in the screening of chronic liver disease among the general community population].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2021
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rebecca HarrisNational Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, UK.ORCID https://orcid.org/0000-0002-7863-7701
Timothy R CardDivision of Epidemiology and Public Health, University of Nottingham, UK.
Toby DelahookeLeicester Royal Infirmary, University Hospitals of Leicester NHS Trust, UK.
Guruprasad P AithalNational Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, UK.
I Neil GuhaNational Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, UK.
University of Nottingham · GBLeicester Royal Infirmary · GBNational Institute for Health Research · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTransient elastography is a non-invasive tool which can stratify patients at risk of chronic liver disease. However, a raised body mass index has been independently associated with a failed or unreliable examination.

objectiveThe purpose of this study was to analyse the performance of two probes (M/XL) on a portable transient elastography device within an obese community population.

methodThe method involved a prospective study with recruitment from a primary care practice. Patients identified with a risk factor for chronic liver disease were invited to a community-based risk stratification pathway for transient elastography readings with both probes. A threshold of ≥8.0 kPa defined elevated liver stiffness.

resultsA total of 477 patients attended the pathway. Of the patients, 21% had no valid measurements with the M probe. There was a significant difference between the probes in the proportion achieving ≥10 valid readings (M versus XL probe: 66.2% versus 90.2%;

conclusionThe XL probe on a portable device significantly improves the applicability of transient elastography within a community-based risk stratification pathway.

Indexed as

chronic liver diseasecommunityobesityrisk stratificationTransient elastography

Identifiers

PMID30386610
PMCPMC6206541
OpenAlexW2799694218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.