ArticleJournal of clinical and experimental dentistry2018
Salivary glucose as a non-invasive biomarker of type 2 diabetes mellitus.
Article in Journal of clinical and experimental dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Hydrogel Bead-Based Assay for the Measurement of Protein Biomarkers in Saliva.ACS measurement science au · 2026Article
- Evaluation and Correlation of Blood Glucose and Salivary Glucose in Diabetes and Periodontitis.Journal of pharmacy & bioallied sciences · 2025Article
- Salivary glucose, salivary interleukin-18, glycemic control, and periodontal status in patients with type 2 diabetes mellitus.Scientific reports · 2025Article
- Exploring Saliva as a Sample for Non-Invasive Glycemic Monitoring in Diabetes: A Scoping Review.Biomedicines · 2025Review
- Oral Health and Diabetic Cardiomyopathy: Mechanisms, Biomarkers, and Early Screening Approaches.Journal of inflammation research · 2025Article
- Correlational analysis between salivary and blood glucose levels in individuals with and without diabetes mellitus: a cross-sectional study.Acta odontologica Scandinavica · 2024Article
- Salivary diagnostics: opportunities and challenges.Theranostics · 2024Review
- Evaluation of Salivary Glucose and Salivary Cortisol in Association with Periodontitis in People with Type II Diabetes: A Case-control Study.Current diabetes reviews · 2024Article
- Review
- Willingness for Medical Screening in a Dental Setting-A Pilot Questionnaire Study.International journal of environmental research and public health · 2023Article
- Studies about the Dietary Impact on "Free" Glycation Compounds in Human Saliva.Foods (Basel, Switzerland) · 2022Article
- Novel impacts of saliva with regard to oral health.The Journal of prosthetic dentistry · 2022Review
- Colorimetric and Electrochemical Screening for Early Detection of Diabetes Mellitus and Diabetic Retinopathy-Application of Sensor Arrays and Machine Learning.Sensors (Basel, Switzerland) · 2022Review
- Comparative Analysis of Fasting Blood Glucose and Salivary Electrolytes Concentrations among Individuals with Type II Diabetes: A Randomized Controlled Hospital Based Study.Toxicology reports · 2022Article
- Changes in Salivary Amylase and Glucose in Diabetes: A Scoping Review.Diagnostics (Basel, Switzerland) · 2021Article
- MicroRNA-1323 serves as a biomarker in gestational diabetes mellitus and aggravates high glucose-induced inhibition of trophoblast cell viability by suppressing TP53INP1.Experimental and therapeutic medicine · 2021Article
- Keyes Triad in Type 2 Diabetes Mellitus: A Microbiological Study.Advanced biomedical research · 2021Article
- Layered Double Hydroxide-Modified Organic Electrochemical Transistor for Glucose and Lactate Biosensing.Sensors (Basel, Switzerland) · 2020Article
- Homocysteine and the Risk of Cardiovascular Events and All-Cause Death in Elderly Population: A Community-Based Prospective Cohort Study.Therapeutics and clinical risk management · 2020Article
- Effectiveness of Salivary Glucose in Diagnosing Gestational Diabetes Mellitus.Contemporary clinical dentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvery year, millions of people are diagnosed with Diabetes mellitus (DM) and the number of new and undiagnosed cases continue to rise. Diagnosis of diabetes is usually performed by blood glucose analysis after fasting for a certain period. However, this method uses an invasive technique that can cause discomfort and even trauma to some patients which could eventually lead to behavioral changes such as avoidance of healthcare and laboratory testing. Studies that explore the diagnostic value of salivary glucose are promising due to the non-invasiveness of the test procedures and its potential correlation with blood results. MATERIAL AND
methodsThe study conducted aimed to determine if salivary glucose can be utilized as an alternative to blood glucose in the screening, diagnosis, and monitoring of type 2 diabetes mellitus (T2DM). A total of 75 participants were recruited and equally divided into 3 groups (normal fasting glucose, impaired fasting glucose, and provisional DM) based on their fasting blood glucose (FBG) level. Blood and unstimulated saliva were collected from each participant and were subjected to glucose analysis using the routine glucose oxidase-peroxidase method.
resultsUsing Pearson's correlation and linear regression, a high degree and significant correlation was observed between blood and salivary glucose (r = 0.715,
conclusionsSalivary glucose is comparable to blood glucose in diagnosing and monitoring T2DM and is considered more advantageous than blood due to its non-invasive nature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.