Evidence map›Paper›PMID 30386502›Full record

ArticleJournal of clinical and experimental dentistry2018

Effectiveness of an erbium-doped: yttrium, aluminum and garnet laser for treatment of peri-implant disease: Clinical, microbiological, and biochemical marker analyses.

Yasutaka Komatsu, Takehiko Kubota, Tadashi Yasuda, Tsurayuki Takahashi, Atsuhiko Yamamoto, Tomoo Kono, Hajime Tabata, Kaname Nohno, Toshiaki Shibutani, Makoto Umeda and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical and experimental dentistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Biomarker Expression of Peri-Implantitis Lesions before and after Treatment: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Yasutaka KomatsuDivision of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Takehiko KubotaDivision of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Tadashi YasudaDepartment of Periodontology, Asahi University, School of Dentistry, Gifu, Japan.
Tsurayuki TakahashiDepartment of Periodontology, Osaka Dental University, Osaka, Japan.
Atsuhiko YamamotoDepartment of Periodontology, Asahi University, School of Dentistry, Gifu, Japan.
Tomoo KonoDepartment of Periodontology, Osaka Dental University, Osaka, Japan.
Hajime TabataDepartment of Periodontology, Osaka Dental University, Osaka, Japan.
Kaname NohnoDivision of Preventive Dentistry, Department of Oral Biological Science, Niigata University Graduate school of Medical and Dental Sciences, Niigata, Japan.
Toshiaki ShibutaniDepartment of Periodontology, Asahi University, School of Dentistry, Gifu, Japan.
Makoto UmedaDepartment of Periodontology, Osaka Dental University, Osaka, Japan.
Hiromasa YoshieDivision of Periodontology, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Asahi University · JPNiigata University · JPOsaka Dental University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effectiveness of an erbium-doped: yttrium, aluminum and garnet (Er: YAG) laser (EYL) for the treatment of peri-implant disease (PID) remains unclear. The aim of this study was to compare non-surgical EYL therapy for PID with locally delivered minocycline hydrochloride (MC) ointment therapy by evaluating clinical, microbiological, and biochemical markers. MATERIAL AND

methodsThirty-seven patients with PID were randomly assigned to either the EYL group (n = 18) or the MC group (n = 19). The clinical, microbiological, and biochemical markers at baseline and at 1 and 3 months after treatment were compared between the two groups. Subgingival plaque and peri-implant crevicular fluid (PICF) were collected from the diseased pockets.

resultsIn the EYL group, probing pocket depth (PPD) was significantly decreased after treatment when compared with baseline. On the other hand, in the MC group, there was no significant decrease in PPD after treatment. Specific bacteria associated with PID were not determined. The counts of both Gram-positive and -negative species did not significantly decrease in the EYL group at 3 months after treatment. In the MC group, the counts of almost all bacterial species were significantly decreased after treatment. Biochemical marker analysis of PICF revealed significantly lower levels of metalloproteinase (MMP)-9 in the EYL group, as compared with the MC group at 3 months after treatment (

conclusionsNon-surgical therapy with an EYL for PID was clinically effective, with decreased MMP-9 levels in PICF, which may lead to reduced peri-implant tissue destruction.

Identifiers

PMID30386502
PMCPMC6203910
OpenAlexW2895520684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.