ArticleWorld journal of radiology2018
Low-radiation and high image quality coronary computed tomography angiography in "real-world" unselected patients.
Article in World journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Evolving Role of Coronary CT Angiography in Coronary Angiography and Intervention: A State-of-the-Art Review.Current cardiology reports · 2024Review
- Review
- The Cost Effectiveness of Coronary CT Angiography and the Effective Utilization of CT-Fractional Flow Reserve in the Diagnosis of Coronary Artery Disease.Journal of cardiovascular development and disease · 2023Review
- A comparison of the use of contrast media with different iodine concentrations for enhanced computed tomography.Frontiers in physiology · 2023Article
- Coronary artery disease imaging reporting and data system (CAD-RADS): what radiologists need to know?Emergency radiology · 2021Review
- Ten things to know about ten imaging studies: A preventive cardiology perspective ("ASPC top ten imaging").American journal of preventive cardiology · 2021Review
- The Incremental Role of Coronary Computed Tomography in Chronic Coronary Syndromes.Journal of clinical medicine · 2020Review
- The sub-millisievert era in CTCA: the technical basis of the new radiation dose approach.La Radiologia medica · 2020Review
- Clinical Applications of Wide-Detector CT Scanners for Cardiothoracic Imaging: An Update.Korean journal of radiology · 2019Review
- Low-Dose Radiation Advances in Coronary Computed Tomography Angiography in the Diagnosis of Coronary Artery Disease.Current cardiology reviews · 2019Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo determine the radiation dose and image quality in coronary computed tomography angiography (CCTA) using state-of-the-art dose reduction methods in unselected "real world" patients.
methodsIn this single-centre study, consecutive patients in sinus rhythm underwent CCTA for suspected coronary artery disease (CAD) using a 320-row detector CT scanner. All patients underwent the standard CT acquisition protocol at our institute (Morriston Hospital) a combination of dose saving advances including prospective electrocardiogram-gating, automated tube current modulation, tube voltage reduction, heart rate reduction, and the most recent novel adaptive iterative dose reconstruction 3D (AIDR3D) algorithm. The cohort comprised real-world patients for routine CCTA who were not selected on age, body mass index, or heart rate. Subjective image quality was graded on a 4-point scale (4 = excellent, 1 = non-diagnostic).
resultsA total of 543 patients were included in the study with a mean body weight of 81 ± 18 kg and a pre-scan mean heart rate of 70 ± 11 beats per minute (bpm). When indicated, patients received rate-limiting medication with an oral beta-blocker followed by additional intravenous beta-blocker to achieve a heart rate below 65 bpm. The median effective radiation dose was 0.88 mSv (IQR, 0.6-1.4 mSv) derived from a Dose Length Product of 61.45 mGy.cm (IQR, 42.86-100.00 mGy.cm). This also includes what we believe to be the lowest ever-reported radiation dose for a routine clinical CCTA (0.18 mSv). The mean image quality (± SD) was 3.65 ± 0.61, with a subjective image quality score of 3 ("good") or above for 93% of patient CCTAs.
conclusionCombining a low-dose scan protocol and AIDR3D with a 320-detector row CT scanner can provide high quality images at exceptionally low radiation dose in unselected patients being investigated for CAD.
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