Evidence map›Paper›PMID 30386458›Full record

ReviewWorld journal of hepatology2018

Aberrant expression of alternative isoforms of transcription factors in hepatocellular carcinoma.

Olga Krivtsova, Anna Makarova, Natalia Lazarevich

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Olga KrivtsovaFederal State Budgetary Institution, "N. N. Blokhin Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation, Moscow 115478, Russian.
Anna MakarovaFederal State Budgetary Institution, "N. N. Blokhin Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation, Moscow 115478, Russian.
Natalia LazarevichFederal State Budgetary Institution, "N. N. Blokhin Medical Research Center of Oncology" of the Ministry of Health of the Russian Federation, Moscow 115478, Russian.
Ministry of Health of the Russian Federation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide and the second leading cause of death among all cancer types. Deregulation of the networks of tissue-specific transcription factors (TFs) observed in HCC leads to profound changes in the hepatic transcriptional program that facilitates tumor progression. In addition, recent reports suggest that substantial aberrations in the production of TF isoforms occur in HCC.

Indexed as

Alternative isoformsAlternative splicingHepatic differentiationHepatocellular carcinomaPersonalized treatmentTranscription factors

Identifiers

PMID30386458
PMCPMC6206146
OpenAlexW2898568907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.