Evidence map›Paper›PMID 30386335›Full record

ReviewFrontiers in immunology2018

From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology.

Ibrahim Al Bakir, Kit Curtius, Trevor A Graham

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Postbiotic potential of heat-inactivated Limosilactobacillus reuteri and its cell-free supernatant in protecting intestinal health of zebrafish.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
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  12. Root Extract ofFrontiers in pharmacology · 2021
    Article
  13. Dietary intake of fermented kimchi prevented colitis-associated cancer.Journal of clinical biochemistry and nutrition · 2020
    Article
  14. Review
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  19. Pathological and immunohistochemical study of colon cancer. Evaluation of markers for colon cancer stem cells.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ibrahim Al BakirEvolution and Cancer Laboratory, Centre for Tumour Biology, Barts Cancer Institute, London, United Kingdom.
Kit CurtiusEvolution and Cancer Laboratory, Centre for Tumour Biology, Barts Cancer Institute, London, United Kingdom.
Trevor A GrahamEvolution and Cancer Laboratory, Centre for Tumour Biology, Barts Cancer Institute, London, United Kingdom.
Institute of Cancer Research · GBSt Mark's Hospital · GB

Funding

Medical Research Council MR/P00122X/1Medical Research Council MR/S003851/1
6 · The paper itself

Abstract

Patients with inflammatory bowel disease have an increased risk of developing colorectal cancer, and this risk is related to disease duration, extent, and cumulative inflammation burden. Carcinogenesis follows the principles of Darwinian evolution, whereby somatic cells acquire genomic alterations that provide them with a survival and/or growth advantage. Colitis represents a unique situation whereby routine surveillance endoscopy provides a serendipitous opportunity to observe somatic evolution over space and time

Indexed as

Cell Transformation, NeoplasticDisease SusceptibilityModels, BiologicalAnimalsBiomarkersClonal EvolutionColitisColorectal NeoplasmsDisease Models, AnimalGenetic Predisposition to DiseaseHumansInflammatory Bowel DiseasesPhenotypeRisk AssessmentRisk FactorsBiomarkersbiomarker developmentcancer evolutioncolorectal cancerinflammatory bowel disease (IBD)risk stratificationsurveillance colonoscopy

Identifiers

PMID30386335
PMCPMC6198656
OpenAlexW2896361583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.