Evidence map›Paper›PMID 30386251›Full record

ArticleFrontiers in physiology2018

Salivary Oxidant/Antioxidant Status in Chronic Temporomandibular Disorders Is Dependent on Source and Intensity of Pain - A Pilot Study.

Ema Vrbanović, Iva Z Alajbeg, Lea Vuletić, Ivana Lapić, Dunja Rogić, Ana Andabak Rogulj, Davor Illeš, Dubravka Knezović Zlatarić, Tomislav Badel, Ivan Alajbeg

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04694274 (Genetic Polymorphisms and Their Association With Temporomandibular Disorders), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04694274 unknown statusnot on this map

Genetic Polymorphisms and Their Association With Temporomandibular Disorders

TypeobservationalSponsorCroatian Science FoundationRan2017 to 2025Enrolled60ConditionsTemporomandibular Disorders, Orofacial PainArmsstabilization splint, physical therapy, placebo splint
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  3. The relationship between oxidative stress markers and temporomandibular disorders: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ema VrbanovićDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Iva Z AlajbegDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Lea VuletićDepartment of Physiology, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Ivana LapićDepartment of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, Croatia.
Dunja RogićDepartment of Laboratory Diagnostics, University Hospital Center Zagreb, Zagreb, Croatia.
Ana Andabak RoguljDepartment of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Davor IllešDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Dubravka Knezović ZlatarićDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Tomislav BadelDepartment of Removable Prosthodontics, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
Ivan AlajbegDepartment of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.
University of Zagreb · HRUniversity Hospital Centre Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Temporomandibular disorders (TMD) have been associated with altered salivary oxidative status, but the relation with pain source and pain severity isn't clarified. With the aim to assess their interaction with TMD, we compared levels of selected salivary oxidative stress (OS) markers (glutathione peroxidase, superoxide dismutase, total antioxidant capacity (TAC), uric acid, 8-hydroxydeoxyguanosine, malondialdehyde) and salivary cortisol (SC) as a stress indicator, between 20 TMD patients and 15 healthy control subjects. In order to record differences relating to pain source and severity, patients were respectively classified according to specific diagnoses (myofascial pain or disc displacement (DD)), and pain intensity (high or low). TAC was significantly higher in TMD patients than in controls (morning

Indexed as

antioxidantscortisolorofacial painoxidative stresssalivary diagnosticstemporomandibular disorders

Identifiers

PMID30386251
PMCPMC6199384
OpenAlexW2895840193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.