ReviewFrontiers in systems neuroscience2018
Cognitive and Physiologic Impacts of the Infraslow Oscillation.
Review in Frontiers in systems neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sex differences in electrical activity of the brain during sleep: a systematic review of electroencephalographic findings across the human lifespan.Biomedical engineering online · 2025Pooled it
- Infraslow Closed-Loop Brain Training for Anxiety and Depression (ISAD): A pilot randomised, sham-controlled trial in adult females with internalizing disorders.Cognitive, affective & behavioral neuroscience · 2025Trial
- Exploring electroencephalographic infraslow neurofeedback treatment for chronic low back pain: a double-blinded safety and feasibility randomized placebo-controlled trial.Scientific reports · 2023Trial
- The infraslow fluctuation of sigma power during sleep and its links to markers of arousal and memory reactivation across development.Scientific reports · 2026Article
- Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals.Nature neuroscience · 2026Article
- Slow-Oscillation Neurofeedback: A Narrative Review on Clinical Efficacy in Pediatric Settings.Behavioral sciences (Basel, Switzerland) · 2026Review
- Data driven multiscale modelling of paroxysmal brain transitions using DC-coupled electrophysiological data.PloS one · 2026Article
- Infra-slow EEG neurofeedback for insomnia: a single-case experimental study in primary care.Frontiers in human neuroscience · 2026Article
- Neurovascular Signaling at the Gliovascular Interface: From Flow Regulation to Cognitive Energy Coupling.International journal of molecular sciences · 2025Review
- Noradrenergic Slow Vasomotion: The Hidden Fluid Pump Linking Sleep, Brain Clearance, and Dementia Pathogenesis.International journal of molecular sciences · 2025Review
- Long Exhalations as Complementary Treatment for Chronic Pain: A Pilot Study.Journal of clinical medicine · 2025Article
- The Infraslow Fluctuation of Sigma Power During Sleep in Young Individuals with Schizophrenia.bioRxiv : the preprint server for biology · 2025Article
- Transcranial 1064-nm laser photobiomodulation modulates frequency-specific cortical source dynamics and functional connectivity in healthy adults.Frontiers in human neuroscience · 2025Article
- Multimodal fNIRS-EEG sensor fusion: Review of data-driven methods and perspective for naturalistic brain imaging.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- A Dynamic Link between Respiration and Arousal.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations.bioRxiv : the preprint server for biology · 2024Article
- Stability of infraslow correlation structure in time-shifted intracranial EEG signals.Frontiers in network physiology · 2024Article
- Hierarchical consciousness: the Nested Observer Windows model.Neuroscience of consciousness · 2024Article
- The temporal structure of REM sleep shows minute-scale fluctuations across brain and body in mice and humans.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Self-regulation training for people with knee osteoarthritis: a protocol for a feasibility randomised control trial (MiNT trial).Frontiers in pain research (Lausanne, Switzerland) · 2023Article
Corrections and comments
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Funding
Abstract
Brain states are traditionally recognized via sleep-wake cycles, but modern neuroscience is beginning to identify many sub-states within these larger arousal types. Multiple lines of converging evidence now point to the infraslow oscillation (ISO) as a mediator of brain sub-states, with impacts ranging from the creation of resting state networks (RSNs) in awake subjects to interruptions in neural activity during sleep. This review will explore first the basic characteristics of the ISO in human subjects before reviewing findings in sleep and in animals. Networks of consistently correlated brain regions known as RSNs seen in human functional neuroimaging studies oscillate together at infraslow frequencies. The infraslow rhythm subdivides nonREM in a manner that may correlate with plasticity. The mechanism of this oscillation may be found in the thalamus and may ultimately come from glial cells. Finally, I review the functional impacts of ISOs on brain phenomena ranging from higher frequency oscillations, to brain networks, to information representation and cognitive performance. ISOs represent a relatively understudied phenomenon with wide effects on the brain and behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.