Evidence map›Paper›PMID 30386187›Full record

ArticleClinical proteomics2018

Proteomic profiling of liver tissue from the

Sandra Murphy, Margit Zweyer, Michael Henry, Paula Meleady, Rustam R Mundegar, Dieter Swandulla, Kay Ohlendieck

Open access · goldAbstract read
In one paragraph

Article in Clinical proteomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Serum protein biomarker signature of Duchenne muscular dystrophy.European journal of translational myology · 2025
    Article
  4. Skeletal muscle disorders as risk factors for type 2 diabetes.Molecular and cellular endocrinology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Sandra MurphyDepartment of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
Margit Zweyer2Institute of Physiology II, University of Bonn, 53115 Bonn, Germany.
Michael Henry3National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.
Paula Meleady3National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland.
Rustam R Mundegar2Institute of Physiology II, University of Bonn, 53115 Bonn, Germany.
Dieter Swandulla2Institute of Physiology II, University of Bonn, 53115 Bonn, Germany.
Kay OhlendieckDepartment of Biology, Maynooth University, National University of Ireland, Maynooth, Co. Kildare, Ireland.
University of Bonn · DEDublin City University · IENational University of Ireland, Maynooth · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuchenne muscular dystrophy is a highly complex multi-system disease caused by primary abnormalities in the membrane cytoskeletal protein dystrophin. Besides progressive skeletal muscle degeneration, this neuromuscular disorder is also associated with pathophysiological perturbations in many other organs including the liver. To determine potential proteome-wide alterations in liver tissue, we have used a comparative and mass spectrometry-based approach to study the dystrophic

methodsThe comparative proteomic profiling of

resultsThe proteomic analysis revealed changes in a variety of protein families, affecting especially fatty acid, carbohydrate and amino acid metabolism, biotransformation, the cellular stress response and ion handling in the

conclusionsThe proteomic results presented here indicate that the intricate and multifaceted pathogenesis of the

Indexed as

DystrophinDystrophinopathyFABP5Fatty acid binding proteinFatty acid metabolismFerritinNeuromuscular disease

Identifiers

PMID30386187
PMCPMC6205794
OpenAlexW2899227423

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.