Evidence map›Paper›PMID 30386110›Full record

ArticleWorld journal of gastroenterology2018

Long term outcome of antiviral therapy in patients with hepatitis B associated decompensated cirrhosis.

Young-Cheol Ju, Dae-Won Jun, Jun Choi, Waqar Khalid Saeed, Hyo-Young Lee, Hyun-Woo Oh

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. [Tenofovir amibufenamide treatment in a case of hepatitis B virus-related decompensated liver cirrhosis].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. [Reversal of cirrhotic decompensation: re-compensation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Young-Cheol JuDepartment of Translational Medicine, Graduate school of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea.
Dae-Won JunDepartment of Translational Medicine, Graduate school of Biomedical Science and Engineering, Hanyang University, Seoul 04763, South Korea.
Jun ChoiDepartment of Industrial Management Engineering, Korea University, Seoul 02841, South Korea.
Waqar Khalid SaeedDepartment of Internal Medicine, School of Medicine, Hanyang University, Seoul 04763, South Korea.
Hyo-Young LeeDepartment of Internal Medicine, School of Medicine, Hanyang University, Seoul 04763, South Korea.
Hyun-Woo OhDepartment of Internal Medicine, School of Medicine, Hanyang University, Seoul 04763, South Korea.
Korea University · KRHanyang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate survival rate and incidence of hepatocellular carcinoma (HCC) in patients with decompensated cirrhosis in the antiviral era.

methodsWe used the Korean Health Insurance Review and Assessment. Korea's health insurance system is a public single-payer system. The study population consisted of 286871 patients who were prescribed hepatitis B antiviral therapy for the first time between 2007 and 2014 in accordance with the insurance guidelines. Overall, 48365 antiviral treatment-naïve patients treated between 2008 and 2009 were included, and each had a follow-up period ≥ 5 years. Data were analyzed for the 1

resultsThe mean patient age was 43.5 years. The annual mortality rates were 2.4%-19.1%, and 5-year cumulative mortality rate was 32.6% in 1

conclusionLong term outcome of decompensated cirrhosis treated with antiviral agent improved much, and incidence of hepatocellular carcinoma and mortality sharply decreased after one year treatment.

Indexed as

AdultAntiviral AgentsCarcinoma, HepatocellularFemaleFollow-Up StudiesHepatitis B, ChronicHepatitis B virusHumansIncidenceLiver CirrhosisLiver NeoplasmsMaleMiddle AgedRecurrenceRepublic of KoreaRetrospective StudiesAntiviral AgentsAntiviral agentDecompensated cirrhosisHepatitis BHepatocellular carcinomaMortality

Identifiers

PMID30386110
PMCPMC6209577
OpenAlexW2898280747

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.